Chevalier-Cottin Emma-Pascale, Ashbaugh Hayley, Brooke Nicholas, Gavazzi Gaetan, Santillana Mauricio, Burlet Nansa, Tin Tin Htar Myint
Sanofi Pasteur, Lyon, France.
Department of Epidemiology, UCLA Fielding School of Public Health, UCLA Fielding School of Public Health, South, Los Angeles, CA, USA.
Infect Dis Ther. 2020 Sep;9(3):467-480. doi: 10.1007/s40121-020-00312-7. Epub 2020 Jun 24.
Despite immunisation being one of the greatest medical success stories of the twentieth century, there is a growing lack of confidence in some vaccines. Improving communication about the direct benefits of vaccination as well as its benefits beyond preventing infectious diseases may help regain this lost confidence. A conference was organised at the Fondation Merieux in France to discuss what benefits could be communicated and how innovative digital initiatives can used for communication. During this meeting, a wide range of indirect benefits of vaccination were discussed. For example, influenza vaccination can reduce hospitalisations and deaths in older persons with diabetes by 45% and 38%, respectively, but the link between influenza and complications from underlying chronic non-communicable diseases such as diabetes is frequently underestimated. Vaccination can reduce antimicrobial resistance (AMR), which is growing, by reducing the incidence of infectious disease (though direct and indirect or herd protection), by reducing the number of circulating AMR strains, and by reducing the need for antimicrobial use. Disease morbidity and treatment costs in the elderly population are likely to rise substantially, with the ageing global population. Healthy ageing and life-course vaccination approaches can reduce the burden of vaccine-preventable diseases, such as seasonal influenza and pneumococcal diseases, which place a significant burden on individuals and society, while improving quality of life. Novel disease surveillance systems based on information from Internet search engines, mobile phone apps, social media, cloud-based electronic health records, and crowd-sourced systems, contribute to improved awareness of disease burden. Examples of the role of new techniques and tools to process data generated by multiple sources, such as artificial intelligence, to support vaccination programmes, such as influenza and dengue, were discussed. The conference participants agreed that continual efforts are needed from all stakeholders to ensure effective, transparent communication of the full benefits and risks of vaccination.
尽管免疫接种是20世纪最伟大的医学成就之一，但人们对某些疫苗的信心却在不断下降。加强关于疫苗接种直接益处以及预防传染病之外益处的沟通，可能有助于重拾这份已丧失的信心。法国梅里埃基金会组织了一次会议，讨论可以传达哪些益处以及如何利用创新数字举措进行沟通。在这次会议上，讨论了疫苗接种的一系列间接益处。例如，流感疫苗接种可分别将患有糖尿病的老年人的住院率和死亡率降低45%和38%，但流感与糖尿病等潜在慢性非传染性疾病并发症之间的联系常常被低估。疫苗接种可通过降低传染病发病率（通过直接和间接或群体保护）、减少循环中的抗微生物耐药菌株数量以及减少对抗微生物药物的使用需求，来降低日益增长的抗微生物药物耐药性（AMR）。随着全球人口老龄化，老年人群体中的疾病发病率和治疗成本可能会大幅上升。健康老龄化和全生命周期疫苗接种方法可减轻季节性流感和肺炎球菌疾病等疫苗可预防疾病的负担，这些疾病给个人和社会带来了巨大负担，同时提高生活质量。基于互联网搜索引擎、手机应用程序、社交媒体、基于云的电子健康记录和众包系统信息的新型疾病监测系统，有助于提高对疾病负担的认识。会议还讨论了利用人工智能等新技术和工具处理多源数据以支持流感和登革热等疫苗接种计划的实例。与会者一致认为，所有利益相关者都需要持续努力，以确保有效、透明地传达疫苗接种的全部益处和风险。
