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[运动作为癫痫的一种治疗策略:文献综述]

[Exercise as a therapeutic strategy in epilepsy: a literature review].

作者信息

Cartagena Y, Cardona-Gallón D C, Isaza S P, Ladino L D

机构信息

Universidad de Antioquia, Facultad de Medicina, Medellín, Colombia.

Universidad de Antioquia. Facultad de Medicina, Medellín, Colombia.

出版信息

Rev Neurol. 2020 Jul 1;71(1):31-37. doi: 10.33588/rn.7101.2020028.

DOI:10.33588/rn.7101.2020028
PMID:32583413
Abstract

INTRODUCTION

Epilepsy is a common neurologic disease with emotional and physical consequences. Thirty percent of patients have drug-resistant epilepsy, therefore adjuvant non-pharmacological therapies, such as physical activity, have been proposed.

AIM

This study reviews the literature about physical activity in people with epilepsy, to evaluate the benefits, potential side effects, impact on comorbidities, the risk classification of sports, and the barriers to their practice.

DEVELOPMENT

Multiple animal and human models evaluate the benefits of exercise in epilepsy, explained by modulation on neurotransmitters, hormones, and neurotrophic factors. Furthermore, exercise demonstrates positive impact on comorbidities such as obesity, cardiovascular disease, depression, and osteoporosis. Despite being a practice that has been shown to be safe, people with epilepsy are less physically active due to barriers that limit their practice.

CONCLUSIONS

Physical activity is beneficial and safe for people with epilepsy. Literature suggests better control of seizures, psychosocial benefits, and improvements on the comorbidities. There is a low risk of injury associated. Exercise should be promoted after a careful clinical evaluation, considering seizure control in the last year, potential triggering factors and the sport chosen.

摘要

引言

癫痫是一种常见的神经系统疾病,会对情绪和身体造成影响。30%的患者患有药物难治性癫痫,因此有人提出了辅助非药物治疗方法,如体育活动。

目的

本研究回顾了有关癫痫患者体育活动的文献,以评估其益处、潜在副作用、对合并症的影响、运动的风险分类以及实施体育活动的障碍。

进展

多种动物和人体模型评估了运动对癫痫的益处,这可以通过对神经递质、激素和神经营养因子的调节来解释。此外,运动对肥胖、心血管疾病、抑郁症和骨质疏松症等合并症具有积极影响。尽管已证明体育活动是安全的,但癫痫患者由于存在限制其进行体育活动的障碍,其身体活动较少。

结论

体育活动对癫痫患者有益且安全。文献表明,体育活动有助于更好地控制癫痫发作,带来心理社会益处,并改善合并症。受伤风险较低。在进行仔细的临床评估后,应根据患者去年的癫痫发作控制情况、潜在触发因素和所选运动来推广体育活动。

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[Exercise as a therapeutic strategy in epilepsy: a literature review].[运动作为癫痫的一种治疗策略:文献综述]
Rev Neurol. 2020 Jul 1;71(1):31-37. doi: 10.33588/rn.7101.2020028.
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Hypothalamic hamartomas in adulthood: Clinical spectrum and treatment outcome-A unicenter experience.成人下丘脑错构瘤:临床谱和治疗结果-单中心经验。
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Epilepsy, seizures, physical exercise, and sports: A report from the ILAE Task Force on Sports and Epilepsy.癫痫、发作、体育锻炼与运动:国际抗癫痫联盟运动与癫痫特别工作组报告
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[Not Available].[无可用内容]。
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J Clin Med. 2025 Apr 15;14(8):2716. doi: 10.3390/jcm14082716.
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Epileptologists' attitudes toward physical exercise and sports for persons with epilepsy in China.中国癫痫专家对癫痫患者体育锻炼和运动的态度。
Epilepsy Behav Rep. 2024 Jun 1;27:100685. doi: 10.1016/j.ebr.2024.100685. eCollection 2024.
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Physical activity in adults with epilepsy: clinical aspects and relationship with cognition and quality of life.癫痫成人的身体活动:临床方面及其与认知和生活质量的关系。
Dement Neuropsychol. 2023 Jul 24;17:e20220107. doi: 10.1590/1980-5764-DN-2022-0107. eCollection 2023.
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Exercise Improved the Anti-Epileptic Effect of Carbamazepine through GABA Enhancement in Epileptic Rats.运动通过增强癫痫大鼠的γ-氨基丁酸(GABA)改善卡马西平的抗癫痫作用。
Neurochem Res. 2021 Aug;46(8):2112-2130. doi: 10.1007/s11064-021-03349-3. Epub 2021 May 19.