Mationg Mary Lorraine S, Williams Gail M, Tallo Veronica L, Olveda Remigio M, Aung Eindra, Alday Portia, Reñosa Mark Donald, Daga Chona Mae, Landicho Jhoys, Demonteverde Maria Paz, Santos Eunice Dianne, Bravo Thea Andrea, Angly Bieri Franziska A, Li Yuesheng, Clements Archie C A, Steinmann Peter, Halton Kate, Stewart Donald E, McManus Donald P, Gray Darren J
Research School of Population Heath, The Australian National University, Canberra, Australia.
Department of Epidemiology and Biostatistics, Research Institute for Tropical Medicine, Manila, Philippines.
JMIR Res Protoc. 2020 Jun 25;9(6):e18419. doi: 10.2196/18419.
Repeated mass drug administration (MDA) of antihelminthics to at-risk populations is still the main strategy for the control of soil-transmitted helminth (STH) infections. However, MDA, as a stand-alone intervention, does not prevent reinfection. Accordingly, complementary measures to prevent STH reinfection, such as health education and improved sanitation, as part of an integrated control approach, are required to augment the effectiveness of MDA for optimal efficiency and sustainability.
The aim of this study is to determine the impact and generalizability of a school-based health education package entitled The Magic Glasses for STH prevention in the Philippines.
We conducted a cluster randomized controlled intervention trial, involving 2020 schoolchildren aged 9-10 years, in 40 schools in Laguna Province, Philippines, to evaluate the impact of the school-based health education package for the prevention of STHs. The trial was conducted over the course of 1 year (June 2016 to July 2017). A total of 20 schools were randomly assigned to the intervention arm, in which The Magic Glasses Philippines health education package was delivered with the standard health education activities endorsed by the Philippines Department of Health (DOH) and the Department of Education (DepEd). The other 20 schools comprised the control arm of the study, where the DOH/DepEd's standard health education activities were done. At baseline, parasitological assessments and a knowledge, attitude, and practice survey were carried out in all schools. In addition, height, weight, and hemoglobin levels were obtained from each child (after parental consent), and their school attendance and academic performance in English and mathematics were accessed from the school records. The baseline and 2 follow-up surveys were completed using the same study measurements and quality-control assessments.
Key results from this cluster randomized intervention trial will shed light on the impact that The Magic Glasses health education package will have against STH infections in schoolchildren in the province of Laguna, located on the Island of Luzon, in the Calabarzon Region of the Philippines.
The results of the trial will be used to assess the generalizability of the impact of The Magic Glasses health education package in different epidemiological and cultural settings, providing evidence for translation of this health education package into public health policy and practice in the Asian region and beyond.
Australian New Zealand Clinical Trials Registry number ACTRN12616000508471; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=368849.
INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/18419.
对高危人群反复进行抗蠕虫药物群体给药（MDA）仍是控制土源性蠕虫（STH）感染的主要策略。然而，MDA作为一种单独的干预措施，并不能预防再感染。因此，需要采取补充措施，如健康教育和改善环境卫生，作为综合控制方法的一部分，以增强MDA的有效性，实现最佳效率和可持续性。
本研究旨在确定名为《预防STH的魔法眼镜》的菲律宾学校健康教育套餐的影响和推广性。
我们在菲律宾拉古纳省的40所学校开展了一项整群随机对照干预试验，涉及2020名9至10岁的学童，以评估该学校健康教育套餐对预防STH的影响。该试验为期1年（2016年6月至2017年7月）。总共20所学校被随机分配到干预组，在该组中，《菲律宾魔法眼镜》健康教育套餐与菲律宾卫生部（DOH）和教育部（DepEd）认可的标准健康教育活动一起实施。另外20所学校构成研究的对照组，在该组中开展DOH/DepEd的标准健康教育活动。在基线时，对所有学校进行寄生虫学评估以及知识、态度和行为调查。此外，在获得家长同意后，获取每个孩子的身高、体重和血红蛋白水平，并从学校记录中获取他们的出勤情况以及英语和数学学科成绩。基线调查和两次随访调查均使用相同的研究测量方法和质量控制评估。
这项整群随机干预试验的主要结果将揭示《魔法眼镜》健康教育套餐对菲律宾甲拉巴松地区吕宋岛拉古纳省学童STH感染的影响。
该试验结果将用于评估《魔法眼镜》健康教育套餐在不同流行病学和文化背景下影响的推广性，为将该健康教育套餐转化为亚洲及其他地区的公共卫生政策和实践提供证据。
澳大利亚新西兰临床试验注册中心编号ACTRN12616000508471；https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=368849。
国际注册报告识别号（IRRID）：DERR1-10.2196/18419。
