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土壤传播蠕虫控制策略的批判性评估

A Critical Appraisal of Control Strategies for Soil-Transmitted Helminths.

作者信息

Campbell Suzy J, Nery Susana V, McCarthy James S, Gray Darren J, Soares Magalhães Ricardo J, Clements Archie C A

机构信息

Research School of Population Health, College of Medicine, Biology, and Environment, The Australian National University, Canberra, Australia.

Research School of Population Health, College of Medicine, Biology, and Environment, The Australian National University, Canberra, Australia.

出版信息

Trends Parasitol. 2016 Feb;32(2):97-107. doi: 10.1016/j.pt.2015.10.006. Epub 2016 Jan 12.

DOI:10.1016/j.pt.2015.10.006
PMID:26795294
Abstract

Interventions that lead to reductions in soil-transmitted helminths (STHs) include chemotherapy with anthelmintic drugs and improvements in water, sanitation, and hygiene (WASH). In this opinion article we aim to determine the evidence for optimal approaches for STH control. First we explore the evidence for the above interventions. We then appraise two integration strategies: current chemotherapy-oriented integrated neglected tropical disease (NTD) control and expanded 'multicomponent integration', which includes integrated chemotherapy, WASH, and other intervention strategies. While multicomponent integrated control may be an effective approach to sustainably reduce STH transmission, there is a need for evidence to prove the feasibility of this approach.

摘要

能够减少土壤传播性蠕虫(STH)感染的干预措施包括使用驱虫药物进行化疗以及改善水、环境卫生和个人卫生(WASH)。在这篇观点文章中,我们旨在确定控制STH的最佳方法的证据。首先,我们探讨上述干预措施的证据。然后,我们评估两种整合策略:当前以化疗为导向的综合被忽视热带病(NTD)控制以及扩展的“多组分整合”,其中包括综合化疗、WASH和其他干预策略。虽然多组分综合控制可能是可持续减少STH传播的有效方法,但需要有证据来证明这种方法的可行性。

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