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眼表面的稳态和防御。结膜微生物组。

Homeostasis and Defense at the Surface of the Eye. The Conjunctival Microbiota.

机构信息

Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center , El Paso, TX, USA.

The Jackson Laboratory for Genomic Medicine , Farmington, CT, USA.

出版信息

Curr Eye Res. 2021 Jan;46(1):1-6. doi: 10.1080/02713683.2020.1788100. Epub 2020 Jul 9.

Abstract

The literature on ocular microbiome has grown tremendously over the past decade, and our knowledge of the different aspects and roles in homeostasis and protection is continuously growing. The development of 16 S rRNA sequencing has allowed the field to characterize communities of bacteria in health and ocular disease. Efforts should continue to further elucidate the interplay between microbiome and key players, such as age, comorbidities, and contact lens usage in order to have better control of the sight-threatening complications.

摘要

过去十年中,眼微生物组学的文献数量大幅增长,我们对其在体内平衡和保护方面的不同方面和作用的了解也在不断增加。16S rRNA 测序的发展使得该领域能够对健康和眼部疾病中的细菌群落进行特征描述。应继续努力进一步阐明微生物组与关键因素(如年龄、合并症和隐形眼镜使用)之间的相互作用,以便更好地控制威胁视力的并发症。

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