鼻咽拭子和唾液检测严重急性呼吸综合征冠状病毒 2 的敏感性。
Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2.
机构信息
Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada.
Sinai Health System, Toronto, Canada.
出版信息
Clin Infect Dis. 2021 Mar 15;72(6):1064-1066. doi: 10.1093/cid/ciaa848.
Abstract
We enrolled 91 consecutive inpatients with COVID-19 at 6 hospitals in Toronto, Canada, and tested 1 nasopharyngeal swab/saliva sample pair from each patient using real-time RT-PCR for severe acute respiratory syndrome coronavirus 2. Sensitivity was 89% for nasopharyngeal swabs and 72% for saliva (P = .02). Difference in sensitivity was greatest for sample pairs collected later in illness.
摘要
我们在加拿大多伦多的 6 家医院招募了 91 名连续住院的 COVID-19 患者，并使用实时 RT-PCR 对每位患者的 1 对鼻咽拭子/唾液样本进行检测，以检测严重急性呼吸综合征冠状病毒 2。鼻咽拭子的敏感性为 89%，唾液为 72%（P =.02）。在疾病后期采集的样本对之间的敏感性差异最大。
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