中鼻甲拭子与鼻咽拭子检测严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）的敏感性。
Sensitivity of midturbinate versus nasopharyngeal swabs for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
机构信息
Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada.
Sinai Health System, Toronto, Canada.
出版信息
Infect Control Hosp Epidemiol. 2021 Aug;42(8):1001-1003. doi: 10.1017/ice.2020.1326. Epub 2020 Nov 18.
Abstract
To compare sensitivity of specimens for COVID-19 diagnosis, we tested 151 nasopharyngeal/midturbinate swab pairs from 117 COVID-19 inpatients using reverse-transcriptase polymerase chain reaction (RT-PCR). Sensitivity was 94% for nasopharyngeal and 75% for midturbinate swabs (P = .0001). In 88 nasopharyngeal/midturbinate pairs with matched saliva, sensitivity was 86% for nasopharyngeal swabs and 88% for combined midturbinate swabs/saliva.
摘要
为了比较用于 COVID-19 诊断的标本的灵敏度，我们使用逆转录聚合酶链反应（RT-PCR）对 117 例 COVID-19 住院患者的 151 对鼻咽/中鼻甲拭子进行了检测。鼻咽拭子的灵敏度为 94%，中鼻甲拭子的灵敏度为 75%（P=.0001）。在 88 对具有匹配唾液的鼻咽/中鼻甲拭子对中，鼻咽拭子的灵敏度为 86%，中鼻甲拭子/唾液的联合灵敏度为 88%。
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