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[肥胖作为2019冠状病毒病的一个风险因素:可能的机制及影响]

[Obesity as a risk factor in COVID-19: Possible mechanisms and implications].

作者信息

Petrova Dafina, Salamanca-Fernández Elena, Rodríguez Barranco Miguel, Navarro Pérez Pilar, Jiménez Moleón José Juan, Sánchez Maria-José

机构信息

Escuela Andaluza de Salud Pública (EASP), Granada, España; Instituto de Investigación Biosanitaria (ibs.GRANADA), Granada, España; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, España.

Escuela Andaluza de Salud Pública (EASP), Granada, España.

出版信息

Aten Primaria. 2020 Aug-Sep;52(7):496-500. doi: 10.1016/j.aprim.2020.05.003. Epub 2020 May 25.

Abstract

Recent reports suggest that obesity is a risk factor for more severe coronavirus disease. This article summarizes the available scientific evidence on the role of obesity in COVID-19. We focus on implications for younger patients and the proposed biological mechanisms that could explain both the higher risk observed and the possible higher contagiousness of people with obesity. We consider implications of the pandemic for people with obesity in relation to: difficulties in managing hospitalized patients, implications of confinement for the control and treatment of obesity, and the stigma people with obesity suffer, that could increase should the relationship between obesity and COVID-19 be confirmed. Understanding the role of obesity in COVID-19 should be a public health priority, given the high prevalence of this condition in our country.

摘要

近期报告表明,肥胖是更严重冠状病毒病的一个风险因素。本文总结了关于肥胖在新冠病毒病中作用的现有科学证据。我们重点关注对年轻患者的影响以及可能解释所观察到的较高风险和肥胖者可能具有更高传染性的生物学机制。我们考虑该大流行病对肥胖者的影响,涉及:管理住院患者的困难、隔离对肥胖控制和治疗的影响,以及肥胖者所遭受的污名化,若肥胖与新冠病毒病之间的关系得到证实,这种污名化可能会加剧。鉴于肥胖在我国的高流行率,了解肥胖在新冠病毒病中的作用应成为公共卫生的优先事项。

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Metabolism. 2020 Jul;108:154251. doi: 10.1016/j.metabol.2020.154251. Epub 2020 Apr 27.
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Obesity and impaired metabolic health in patients with COVID-19.COVID-19 患者的肥胖和代谢健康受损。
Nat Rev Endocrinol. 2020 Jul;16(7):341-342. doi: 10.1038/s41574-020-0364-6.
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Exercise in the time of COVID-19.新冠疫情期间的锻炼
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