Centro de Atención Primaria de Vilanova del Camí, Institut Català de La Salut, Catalunya Central, Vilanova del Camí, Barcelona, Spain.
Health Promotion in Rural Areas Research Group, Gerència Territorial de La Catalunya Central, Institut Català de La Salut, Carrer Pica d'Estats, 36, 08272, Sant Fruitós de Bages, Barcelona, Spain.
Sci Rep. 2022 Jun 2;12(1):9169. doi: 10.1038/s41598-022-13290-2.
To define the seroprevalence of antibodies against SARS-CoV-2 in the municipality of Vilanova del Camí (in the region of Conca d'Ódena, Barcelona, Spain) and to know the risk factors associated with positive seroprevalence. Cross-sectional descriptive study. The population of Vilanova del Camí had the opportunity to voluntarily attend two screenings (October and December 2020) for antibodies against the nucleocapsid protein of SARS-CoV-2 using a Rapid Diagnostic Test (RDT) (Salocor (Salofa Oy). Participants in the screening signed an informed consent form. From the 3,610 attendees at the screening, 2,170 patients were randomly selected. The relationship between antibody test results and other demographic (sex, age, morbidity index) and clinical (diagnoses, smoking and drugs) variables was analysed. The prevalence of antibodies against SARS-CoV-2 was 9.6% (95% CI of 8.4% to 10.9%) and was similar for men and women but increased with age. Among complex chronic patients, 14.3% had antibodies against SARS-CoV-2, and among patients with advanced chronic disease, 25% had antibodies against SARS-CoV-2. Age, AMG (Adjusted Morbidity Groups) index, COVID-19 diagnosis and contact with a COVID-19 case were risk factors for positive seroprevalence. A higher seroprevalence was detected in the October screening (12.16%) than in the December screening (8.38%). In the December screening, obesity was a risk factor for positive seroprevalence. This study demonstrates the high seroprevalence of antibodies against SARS-CoV-2 in the pandemic epicentre of Catalonia.
在西班牙巴塞罗那康卡德奥登纳地区的比拉诺瓦德尔卡米市（Vilanova del Camí）确定针对 SARS-CoV-2 的抗体血清阳性率，并了解与阳性血清阳性率相关的危险因素。横断面描述性研究。比拉诺瓦德尔卡米市的居民有机会自愿参加两次针对 SARS-CoV-2 核衣壳蛋白的抗体筛查（2020 年 10 月和 12 月），使用快速诊断测试（RDT）（Salocor（Salofa Oy）。筛查参与者签署了知情同意书。在参加筛查的 3610 名患者中，随机选择了 2170 名患者。分析了抗体检测结果与其他人口统计学（性别、年龄、发病率指数）和临床（诊断、吸烟和药物）变量之间的关系。针对 SARS-CoV-2 的抗体的流行率为 9.6%（95%置信区间为 8.4%至 10.9%），男性和女性之间相似，但随年龄增长而增加。在复杂的慢性患者中，14.3%有针对 SARS-CoV-2 的抗体，在患有晚期慢性疾病的患者中，有 25%有针对 SARS-CoV-2 的抗体。年龄、AMG（调整发病率组别）指数、COVID-19 诊断和与 COVID-19 病例的接触是血清阳性率的危险因素。10 月筛查（12.16%）的血清阳性率高于 12 月筛查（8.38%）。在 12 月的筛查中，肥胖是血清阳性率的一个危险因素。本研究表明，在加泰罗尼亚大流行中心，针对 SARS-CoV-2 的抗体血清阳性率很高。
