Suppr超能文献

COVID-19 相关的嗅觉丧失与 MRI 显示的嗅球损伤有关。

Anosmia in COVID-19 Associated with Injury to the Olfactory Bulbs Evident on MRI.

机构信息

From the Universidade Federal de Pernambuco (M.F.V.V.A., M.C.L., M.M.V.), Recife, Brazil

Centro Diagnostico Multimagem (M.F.V.V.A.), Recife, Brazil.

出版信息

AJNR Am J Neuroradiol. 2020 Sep;41(9):1703-1706. doi: 10.3174/ajnr.A6675. Epub 2020 Jun 25.

Abstract

Patients with coronavirus disease 2019 (COVID-19) may have symptoms of anosmia or partial loss of the sense of smell, often accompanied by changes in taste. We report 5 cases (3 with anosmia) of adult patients with COVID-19 in whom injury to the olfactory bulbs was interpreted as microbleeding or abnormal enhancement on MR imaging. The patients had persistent headache ( = 4) or motor deficits ( = 1). This olfactory bulb injury may be the mechanism by which the Severe Acute Respiratory Syndrome coronavirus 2 causes olfactory dysfunction.

摘要

新型冠状病毒病 2019(COVID-19)患者可能有嗅觉丧失或部分嗅觉丧失的症状,常伴有味觉改变。我们报告了 5 例(3 例有嗅觉丧失)COVID-19 成年患者,其嗅球损伤被解释为磁共振成像上的微出血或异常增强。患者持续头痛(=4)或运动功能障碍(=1)。这种嗅球损伤可能是严重急性呼吸综合征冠状病毒 2 导致嗅觉功能障碍的机制。

相似文献

1
Anosmia in COVID-19 Associated with Injury to the Olfactory Bulbs Evident on MRI.
AJNR Am J Neuroradiol. 2020 Sep;41(9):1703-1706. doi: 10.3174/ajnr.A6675. Epub 2020 Jun 25.
2
Olfactory Bulb Magnetic Resonance Imaging in SARS-CoV-2-Induced Anosmia: The First Report.
Acad Radiol. 2020 Jun;27(6):892-893. doi: 10.1016/j.acra.2020.04.002. Epub 2020 Apr 11.
3
Bilateral transient olfactory bulb edema during COVID-19-related anosmia.
Neurology. 2020 Aug 4;95(5):224-225. doi: 10.1212/WNL.0000000000009850. Epub 2020 May 22.
4
Olfactory Bulb Signal Abnormality in Patients with COVID-19 Who Present with Neurologic Symptoms.
AJNR Am J Neuroradiol. 2020 Oct;41(10):1882-1887. doi: 10.3174/ajnr.A6751. Epub 2020 Aug 27.
6
Olfactory Dysfunction in the COVID-19 Outbreak.
J Investig Allergol Clin Immunol. 2020;30(5):317-326. doi: 10.18176/jiaci.0567. Epub 2020 May 14.
8
Olfactory Dysfunction and Sinonasal Symptomatology in COVID-19: Prevalence, Severity, Timing, and Associated Characteristics.
Otolaryngol Head Neck Surg. 2020 Jul;163(1):114-120. doi: 10.1177/0194599820929185. Epub 2020 May 19.
10
Smell and taste disorders in Spanish patients with mild COVID-19.
Neurologia (Engl Ed). 2020 Nov-Dec;35(9):633-638. doi: 10.1016/j.nrl.2020.07.006. Epub 2020 Jul 28.

引用本文的文献

2
Changes in olfactory bulb volume and olfactory sulcus depth in COVID-19 infection: an autopsy study.
Eur Arch Otorhinolaryngol. 2025 Feb;282(2):813-819. doi: 10.1007/s00405-024-09077-y. Epub 2024 Nov 23.
4
Polyunsaturated Fatty Acids as Potential Treatments for COVID-19-Induced Anosmia.
Biomedicines. 2024 Sep 12;12(9):2085. doi: 10.3390/biomedicines12092085.
5
A non-invasive AI-based system for precise grading of anosmia in COVID-19 using neuroimaging.
Heliyon. 2024 Jun 12;10(12):e32726. doi: 10.1016/j.heliyon.2024.e32726. eCollection 2024 Jun 30.
6
Long COVID: From olfactory dysfunctions to viral Parkinsonism.
World J Otorhinolaryngol Head Neck Surg. 2024 Apr 8;10(2):137-147. doi: 10.1002/wjo2.175. eCollection 2024 Jun.
7
[Not Available].
Neurol Perspect. 2021 Jul-Sep;1(3):187-188. doi: 10.1016/j.neurop.2021.05.002. Epub 2021 May 28.
8
Alcohol Sniff Test (AST): An Important Tool for Screening Post-Viral Olfactory Loss in Acute Flu-Like Dysfunction.
Indian J Otolaryngol Head Neck Surg. 2024 Feb;76(1):604-610. doi: 10.1007/s12070-023-04224-z. Epub 2023 Sep 30.
10
The impact of Chinese COVID-19 pandemic on the incidence of peripheral facial nerve paralysis after optimizing policies.
Front Public Health. 2023 Nov 2;11:1236985. doi: 10.3389/fpubh.2023.1236985. eCollection 2023.

本文引用的文献

1
SARS-CoV-2 Receptors and Entry Genes Are Expressed in the Human Olfactory Neuroepithelium and Brain.
iScience. 2020 Dec 18;23(12):101839. doi: 10.1016/j.isci.2020.101839. Epub 2020 Nov 25.
2
Bilateral transient olfactory bulb edema during COVID-19-related anosmia.
Neurology. 2020 Aug 4;95(5):224-225. doi: 10.1212/WNL.0000000000009850. Epub 2020 May 22.
3
Hemorrhagic Posterior Reversible Encephalopathy Syndrome as a Manifestation of COVID-19 Infection.
AJNR Am J Neuroradiol. 2020 Jul;41(7):1173-1176. doi: 10.3174/ajnr.A6595. Epub 2020 May 21.
4
Cerebral venous thrombosis associated with COVID-19 infection: Causality or coincidence?
J Neuroradiol. 2021 Mar;48(2):121-124. doi: 10.1016/j.neurad.2020.05.003. Epub 2020 May 11.
5
COVID-19-associated Diffuse Leukoencephalopathy and Microhemorrhages.
Radiology. 2020 Oct;297(1):E223-E227. doi: 10.1148/radiol.2020202040. Epub 2020 May 21.
6
Imaging of Neurologic Disease in Hospitalized Patients with COVID-19: An Italian Multicenter Retrospective Observational Study.
Radiology. 2020 Nov;297(2):E270-E273. doi: 10.1148/radiol.2020201933. Epub 2020 May 21.
7
Isolated Anosmia as a Presentation of COVID-19: An Experience in a Referral Hospital.
Infect Disord Drug Targets. 2020;20(3):350. doi: 10.2174/1871526520999200520173216.
8
Anosmia Is a Key Symptom of COVID-19 Infection and Should Be Used as a Diagnostic Tool.
Ear Nose Throat J. 2020 Nov;99(9):577-578. doi: 10.1177/0145561320925191. Epub 2020 May 21.
9
Neurological manifestations of COVID-19 and other coronavirus infections: A systematic review.
Clin Neurol Neurosurg. 2020 Jul;194:105921. doi: 10.1016/j.clineuro.2020.105921. Epub 2020 May 15.
10
Venous cerebral thrombosis in COVID-19 patient.
J Neurol Sci. 2020 Jul 15;414:116871. doi: 10.1016/j.jns.2020.116871. Epub 2020 May 1.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验