COVID-19 嗅觉丧失患者的磁共振成像显示嗅球异常：初步前瞻性研究。
Magnetic resonance imaging of COVID-19 anosmic patients reveals abnormalities of the olfactory bulb: Preliminary prospective study.
机构信息
Department of Radiology, APHP, Hôpitaux R. Poincaré-Ambroise Paré, DMU Smart Imaging, GH Université Paris-Saclay, U 1179 UVSQ/Paris-Saclay, Paris, France.
Department of Otolaryngology-Head & Neck Surgery, Hopital Foch, Paris Saclay University, UFR Simone Veil, Université Versailles Saint-Quentin-en-Yvelines (Paris Saclay University), Paris, France; Department of Otolaryngology-Head & Neck Surgery, CHU Saint-Pierre (CHU de Bruxelles), Université Libre de Bruxelles, Brussels, Belgium; Department of Human Anatomy and Experimental Oncology, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium.
出版信息
J Infect. 2020 Nov;81(5):816-846. doi: 10.1016/j.jinf.2020.07.028. Epub 2020 Jul 30.
• COVID-19 patients with total loss of smell have more olfactory bulb abnormalities at the magnetic resonance imaging than patients without loss of smell. • The olfactory bulb MRI abnormalities may be objectified through a signal intensity ratio measurement that is calculated between the average signals of the olfactory bulb and the frontal white matter. • The loss of smell is probably due to olfactory bulb inflammation related to virus spread.
• 与嗅觉正常的 COVID-19 患者相比，嗅觉完全丧失的患者的嗅球在磁共振成像中存在更多异常。• 通过计算嗅球和额白质平均信号之间的信号强度比，可以客观化嗅球 MRI 异常。• 嗅觉丧失可能是由于病毒扩散引起的嗅球炎症所致。
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