印度人眼植入可折叠 Collamer 透镜 V4c 后前房角的眼前节光学相干断层扫描研究。
An anterior segment optical coherence tomography study of the anterior chamber angle after implantable collamer lens-V4c implantation in Asian Indian Eyes.
作者信息
Singh Rashmi, Vanathi Murugesan, Kishore Alisha, Tandon Radhika, Singh Divya
机构信息
Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
出版信息
Indian J Ophthalmol. 2020 Jul;68(7):1418-1423. doi: 10.4103/ijo.IJO_1540_19.
PURPOSE
To quantitatively assess anterior chamber and angle parameters by anterior segment optical coherence tomography (AS-OCT) in myopic eyes undergoing Implantable Collamer Lens (ICL V4c) implantation.
METHODS
Prospective noncomparative observational case series. Pre and postoperative (1 and 3 month) AS-OCT angle parameters (anterior chamber depth [ACD], anterior chamber angle [ACA], Angle opening distance [AOD], trabecular iris space area [TISA], scleral spur angle [SSA]) were evaluated in 32 eyes (16 patients). SPSS version 20 with paired t-test for intragroup and Mann-Whitney U value test for intergroup comparisons.
RESULTS
It included 6 (37.5%) males and 10 (62.5%) females. Preoperative ACA of 34.6 ± 2.3° reduced to 32.2 ± 2.4°, 31.9 ± 2.5° at 1 and 3 months postoperatively (P = 0.001). Preoperative mean AOD500, AOD750, TISA500, TISA750, SSA of 0.34 ± 0.06 mm, 0.52 ± 0.15 mm, 0.09 ± 0.02 mm, 0.20 ± 0.04 mm, 34.27 ± 4.6° decreased to 0.32 ± 0.06 mm, 0.48 ± 0.15 mm, 0.08 ± 0.02 mm, 0.17 ± 0.05 mm, 32.5 ± 4.3° at 1-month (P = 0.001); 0.32 ± 0.06 mm, 0.47 ± 0.13 mm, 0.08 ± 0.02 mm, 0.17 ± 0.05 mm and 32.4 ± 4.6° (P = 0.001) at 3-months, respectively. Correlation analysis between preoperative ACD/intraocular pressure (IOP) was - 0.62 (P = 0.0002) [1 month], -0.40 (0.024) [third month]; between IOP/postoperative ACA, AOD500, AOD750, TISA500, TISA750, SSA was - 0.04 (0.81), -0.03 (0.85), -0.08 (0.64), -0.12 (0.48), -0.10 (0.57), -0.06 (0.73) at 1 month; -0.09 (0.58), 0.04 (0.78), 0.12 (0.48), -0.02 (0.9), -0.04 (0.79), 0.02 (0.88) at 3 months; between ICL vault/ACA, AOD500, AOD750, TISA500, TISA750, SSA was 0.38 (0.02), 0.24 (0.17), 0.21 (0.25), 0.05 (0.75), 0.15 (0.41), 0.27 (0.13) at 1 month; 0.19 (0.28), 0.06 (0.71), -0.03 (0.85), 0.005 (0.97), 0.05 (0.78), 0.07 (0.68) at 3 month.
CONCLUSION
Postoperatively significant angle narrowing was noted. There was a negative correlation between IOP and preoperative ACD. There was no significant correlation between IOP and ICL vault with postoperative AS-OCT angle parameters.
目的
通过眼前节光学相干断层扫描（AS-OCT）定量评估近视患者植入可植入 Collamer 透镜（ICL V4c）后的前房和角度参数。
方法
前瞻性非对照观察性病例系列。在 32 只眼（16 例）中评估术前和术后（1 个月和 3 个月）AS-OCT 角度参数（前房深度[ACD]、前房角[ACA]、房角开口距离[AOD]、小梁虹膜空间面积[TISA]、巩膜突角[SSA]）。采用 SPSS 20 版进行组内配对 t 检验和组间曼-惠特尼 U 值检验。
结果
包括 6 名（37.5%）男性和 10 名（62.5%）女性。术前 ACA 为 34.6±2.3°，术后 1 个月和 3 个月分别降至 32.2±2.4°和 31.9±2.5°（P=0.001）。术前平均 AOD500、AOD750、TISA500、TISA750、SSA 分别为 0.34±0.06mm、0.52±0.15mm、0.09±0.02mm、0.20±0.04mm、34.27±4.6°，术后 1 个月和 3 个月分别降至 0.32±0.06mm、0.48±0.15mm、0.08±0.02mm、0.17±0.05mm、32.5±4.3°（P=0.001）；术后 1 个月和 3 个月分别降至 0.32±0.06mm、0.47±0.13mm、0.08±0.02mm、0.17±0.05mm、32.4±4.6°（P=0.001）。术前 ACD/眼压（IOP）与术前 ACD/眼压（IOP）的相关性分析为-0.62（P=0.0002）[1 个月]，-0.40（0.024）[3 个月]；IOP/术后 ACA、AOD500、AOD750、TISA500、TISA750、SSA 之间的相关性分析为-0.04（0.81），-0.03（0.85），-0.08（0.64），-0.12（0.48），-0.10（0.57），-0.06（0.73），IOP/术后 ACA、AOD500、AOD750、TISA500、TISA750、SSA 之间的相关性分析为-0.09（0.58），0.04（0.78），0.12（0.48），-0.02（0.9），-0.04（0.79），0.02（0.88）；ICL 拱高/ACA、AOD500、AOD750、TISA500、TISA750、SSA 之间的相关性分析为 0.38（0.02）、0.24（0.17）、0.21（0.25）、0.05（0.75）、0.15（0.41）、0.27（0.13）。
结论
术后观察到明显的角度变窄。IOP 与术前 ACD 呈负相关。IOP 与术后 AS-OCT 角度参数之间无显著相关性。
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