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耳蜗和前庭传出神经元对[3H]-D-天冬氨酸标记物的逆行运输。

Retrograde transport of [3H]-D-aspartate label by cochlear and vestibular efferent neurons.

作者信息

Schwarz D W, Schwarz I E

机构信息

Division of Otolaryngology, University of British Columbia, Vancouver, Canada.

出版信息

Am J Otolaryngol. 1988 Jan-Feb;9(1):6-11. doi: 10.1016/s0196-0709(88)80002-4.

DOI:10.1016/s0196-0709(88)80002-4
PMID:3258736
Abstract

[3H]-D-aspartic acid was injected into the inner ear of rats. After a six hour survival time, labeled cells were found at all locations known to contain efferent cochlear or vestibular neurons. Most labeled neurons were found in the ipsilateral lateral superior olivary nucleus (LSO), although both ventral nuclei of the trapezoid body (VTB), group E, and the caudal pontine reticular nucleus (CPR) just adjacent to the ascending limb of the facial nerve also contained labeled cells. Because not all efferent neurons in the rat could be previously shown to be cholinergic, aspartate and glutamate are efferent transmitter candidates.

摘要

将[3H]-D-天冬氨酸注射到大鼠内耳中。在存活6小时后,在所有已知含有耳蜗或前庭传出神经元的位置都发现了标记细胞。大多数标记神经元位于同侧外侧上橄榄核(LSO),尽管梯形体腹侧核(VTB)的E组以及紧邻面神经上升支的尾侧脑桥网状核(CPR)也含有标记细胞。由于之前并未证明大鼠所有的传出神经元都是胆碱能的,因此天冬氨酸和谷氨酸是传出递质的候选物。

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Retrograde transport of [3H]-D-aspartate label by cochlear and vestibular efferent neurons.耳蜗和前庭传出神经元对[3H]-D-天冬氨酸标记物的逆行运输。
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