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一只接受手术切除和磷酸托西拉尼治疗的胰腺腺癌猫的长期存活情况。

Long-term survival in a cat with pancreatic adenocarcinoma treated with surgical resection and toceranib phosphate.

作者信息

Todd Johanna E, Nguyen Sandra M

机构信息

Medical Oncology, Small Animal Specialist Hospital, North Ryde, NSW, Australia.

出版信息

JFMS Open Rep. 2020 Jun 12;6(1):2055116920924911. doi: 10.1177/2055116920924911. eCollection 2020 Jan-Jun.

Abstract

CASE SUMMARY

Primary pancreatic adenocarcinoma is an uncommon neoplasm seen in cats and often has a poor prognosis. We report a case of an 8-year-old male neutered domestic shorthair cat weighing 5.8 kg diagnosed with pancreatic adenocarcinoma treated with surgical resection and toceranib phosphate, which had a progression-free interval of 1148 days and survived for more than 1436 days. The treatment was well tolerated; however, the cat developed generalised coat hypopigmentation.

RELEVANCE AND NOVEL INFORMATION

To our knowledge, the cat in our report has the longest progression-free interval and survival time post-surgical resection of pancreatic carcinoma treated with toceranib. Hypopigmentation as a side effect of toceranib has been reported in dogs, but this is the first case reported in cats.

摘要

病例摘要

原发性胰腺腺癌是猫中少见的肿瘤,预后通常较差。我们报告一例8岁、体重5.8千克的已绝育家养短毛雄性猫,诊断为胰腺腺癌,接受了手术切除和磷酸托西拉尼治疗,无进展生存期为1148天,存活超过1436天。该治疗耐受性良好;然而,这只猫出现了全身被毛色素减退。

相关性和新信息

据我们所知,我们报告中的这只猫在接受磷酸托西拉尼治疗的胰腺癌手术切除后,具有最长的无进展生存期和生存时间。托西拉尼的副作用色素减退在犬中已有报道,但这是猫中首次报道的病例。

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