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磷酸托西拉尼(帕拉迪)辅助化疗治疗猫眼眶限制性肌成纤维细胞肉瘤:一例猫的病例研究

Feline restrictive orbital myofibroblastic sarcoma treated with toceranib phosphate (Palladia) as adjuvant chemotherapy: A case study of one cat.

作者信息

Komatsu Hiroyuki, Ueshima Asuka, Kobayashi Yoshitaka, Shimoyama Yumiko, Takiyama Naoaki, Rimpo Kenji

机构信息

Animal Eye Care-Tokyo Animal Eye Clinic Tokyo Japan.

Saitama Animal Medical Center Saitama Japan.

出版信息

Clin Case Rep. 2023 Jun 17;11(6):e7582. doi: 10.1002/ccr3.7582. eCollection 2023 Jun.

DOI:10.1002/ccr3.7582
PMID:37334334
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10276202/
Abstract

KEY CLINICAL MESSAGE

This is the first case report of treatment with toceranib phosphate as postsurgical adjuvant chemotherapy for advanced FROMS. This reported case highlights the need for further studies on the efficacy of toceranib phosphate as adjuvant chemotherapy for FROMS.

ABSTRACT

Feline restrictive orbital myofibroblastic sarcoma (FROMS) is a rare aggressive tumor in cats. We explored the effectiveness of using toceranib phosphate as postsurgical adjuvant chemotherapy for advanced FROMS in a 7-year-old cat. Despite treatment, the cat died 4 months after surgery. This report highlights the need for further studies on the efficacy of toceranib phosphate as adjuvant chemotherapy for FROMS.

摘要

关键临床信息

这是首例使用磷酸托西拉尼作为晚期猫眼眶限制性肌纤维母细胞肉瘤(FROMS)术后辅助化疗的病例报告。该病例报告强调了有必要进一步研究磷酸托西拉尼作为FROMS辅助化疗的疗效。

摘要

猫眼眶限制性肌纤维母细胞肉瘤(FROMS)是猫中一种罕见的侵袭性肿瘤。我们探讨了在一只7岁猫中使用磷酸托西拉尼作为晚期FROMS术后辅助化疗的有效性。尽管进行了治疗,这只猫在手术后4个月死亡。本报告强调了有必要进一步研究磷酸托西拉尼作为FROMS辅助化疗的疗效。

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本文引用的文献

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Sci Rep. 2022 Sep 22;12(1):15791. doi: 10.1038/s41598-022-19089-5.
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Metastatic feline mammary cancer: prognostic factors, outcome and comparison of different treatment modalities - a retrospective multicentre study.猫转移性乳腺肿瘤:预后因素、结果和不同治疗方式的比较——一项回顾性多中心研究。
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Squamous cell carcinoma of the anal sac in two cats.
两只猫的肛囊鳞状细胞癌。
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Long-term survival in a cat with pancreatic adenocarcinoma treated with surgical resection and toceranib phosphate.一只接受手术切除和磷酸托西拉尼治疗的胰腺腺癌猫的长期存活情况。
JFMS Open Rep. 2020 Jun 12;6(1):2055116920924911. doi: 10.1177/2055116920924911. eCollection 2020 Jan-Jun.
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Evaluation of cytology and histopathology for the diagnosis of feline orbital neoplasia: 81 cases (2004-2019) and review of the literature.猫眼眶肿瘤的细胞学和组织病理学诊断评估:81 例病例(2004-2019 年)及文献复习。
Vet Ophthalmol. 2020 Jul;23(4):682-689. doi: 10.1111/vop.12776. Epub 2020 May 15.
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Management of a feline gastric stromal cell tumour with toceranib phosphate: a case study.磷酸托西拉尼治疗猫胃间质细胞瘤:病例报告
Aust Vet J. 2020 May;98(5):181-184. doi: 10.1111/avj.12921. Epub 2020 Jan 23.
7
Phosphorylated KIT as a predictor of outcome in canine mast cell tumours treated with toceranib phosphate or vinblastine.磷酸化 KIT 作为用托昔单抗磷酸盐或长春碱治疗的犬肥大细胞瘤预后的预测指标。
Vet Comp Oncol. 2020 Jun;18(2):169-175. doi: 10.1111/vco.12525. Epub 2019 Oct 21.
8
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Vet Clin North Am Small Anim Pract. 2019 Sep;49(5):917-931. doi: 10.1016/j.cvsm.2019.04.005. Epub 2019 Jun 8.
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Long-term clinical control of feline pancreatic carcinoma with toceranib phosphate.磷酸托西拉尼对猫胰腺癌的长期临床控制
Can Vet J. 2018 Jul;59(7):751-754.
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