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一名感染新型冠状病毒的患者出现吉兰-巴雷综合征:病例报告

Guillain-Barré syndrome in a patient infected with SARS-CoV-2, a case report.

作者信息

Farzi Mohammad Amin, Ayromlou Hormoz, Jahanbakhsh Naser, Bavil Parisa Hadavi, Janzadeh Abdolali, Shayan Farid Karkon

机构信息

Tabriz University of Medical Sciences, Iran.

Tabriz University of Medical Sciences, Iran.

出版信息

J Neuroimmunol. 2020 Sep 15;346:577294. doi: 10.1016/j.jneuroim.2020.577294. Epub 2020 Jun 20.

Abstract

BACKGROUND

The COVID-19 is a novel condition affecting all the world, so every manifestation of disease should be reported. Neurologic manifestations of the disease are increasingly identified and this will help clinician to improve their diagnostic and therapeutic skills in dealing with COVID-19 patients.

CASE

In this article we report a 41-year-old male that developed ascending paresthesia and paralysis following infection with SARS-CoV-2 virus. Electrodiagnostic evaluation in patient revealed demyelinating type polyneuropathy and patient diagnosed as Guillain-Barré syndrome (AIDP type) and treated with IVIG which resulted in favorable response.

CONCLUSIONS

Considering this report and other reports that are mentioned in our short review, there is probably causal relationship between COVID-19 and development of Guillain-Barré syndrome.

摘要

背景

新型冠状病毒肺炎(COVID-19)是一种影响全球的新疾病,因此疾病的每一种表现都应予以报告。该疾病的神经系统表现越来越多地被发现,这将有助于临床医生提高处理COVID-19患者的诊断和治疗技能。

病例

在本文中,我们报告了一名41岁男性,在感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2)病毒后出现上行性感觉异常和麻痹。对该患者的电诊断评估显示为脱髓鞘型多发性神经病,患者被诊断为吉兰-巴雷综合征(急性炎症性脱髓鞘性多发性神经病类型)并接受静脉注射免疫球蛋白治疗,结果反应良好。

结论

考虑到本报告以及我们简短综述中提及的其他报告,COVID-19与吉兰-巴雷综合征的发生之间可能存在因果关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/639e/7305747/dd11ba163ae9/ga1_lrg.jpg

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