Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Department of Neurology, Mayo Clinic, Scottsdale, AZ, USA.
Acta Neurol Belg. 2023 Feb;123(1):9-44. doi: 10.1007/s13760-022-02137-2. Epub 2022 Nov 16.
Despite the advantages of getting access to the coronavirus disease 2019 (COVID-19) vaccines, their potential ability to induce severe adverse events (AEs) has been a significant concern. Neurological complications are significant among the various adverse events following immunization (AEFI) due to their likely durability and debilitating sequelae. Neurological AEs following COVID-19 vaccination can either exacerbate or induce new-onset neuro-immunologic diseases, such as myasthenia gravis (MG) and Guillain-Barre syndrome (GBS). The more severe spectrum of AEs post-COVID19 vaccines has included seizures, reactivation of the varicella-zoster virus, strokes, GBS, Bell's palsy, transverse myelitis (TM), and acute disseminated encephalomyelitis (ADEM). Here, we discuss each of these neurological adverse effects separately.
尽管可以获得 2019 年冠状病毒病（COVID-19）疫苗，但它们潜在的引发严重不良事件（AE）的能力一直是一个重大关注点。由于其可能的持久性和使人虚弱的后遗症，接种疫苗后的神经系统并发症是各种接种后不良事件（AEFI）中的重要并发症。COVID-19 疫苗接种后的神经系统 AE 既可以加重也可以引发新的神经免疫性疾病，例如重症肌无力（MG）和格林-巴利综合征（GBS）。COVID-19 疫苗接种后更严重的 AE 包括癫痫发作、水痘-带状疱疹病毒再激活、中风、GBS、贝尔氏麻痹、横贯性脊髓炎（TM）和急性播散性脑脊髓炎（ADEM）。在这里，我们将分别讨论这些神经系统不良事件。
