Sinadinos Angela, Shelswell Jonathan
Dental Officer, Mid Yorks NHS Foundation trust, Bradford District Care NHS Foundation Trust, UK.
Restorative Dentistry, Leeds Teaching Hospitals NHS Foundation Trust, UK.
Evid Based Dent. 2020 Jun;21(2):49. doi: 10.1038/s41432-020-0100-z.
Design Case series.Introduction The most common signs and symptoms of SARS-CoV-2 infection include headache, sore throat, hyposmia, hypogeusia, diarrhoea, dyspnoea and pneumonia. Dermatological manifestations have also been reported but few authors have documented oral signs and symptoms. Methods Three cases are reported where oral ulceration or blistering is found in patients with confirmed or suspected COVID-19.Results One patient had serologically confirmed COVID-19, whilst the remaining two cases were only suspected. Two patients reported pain from the palate, whilst the third reported in the tongue. The first two patients had lesions affecting keratinised tissue consistent with herpes simplex lesions but with no history of herpetic infection. The third patient had lesions compatible with erythema multiforme.Conclusions The authors suggest a link between COVID-19 and oral ulceration and blistering, but acknowledge these signs may often go undetected due to a lack of intraoral examination during hospital admission.
设计 病例系列。引言 严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染最常见的体征和症状包括头痛、咽痛、嗅觉减退、味觉减退、腹泻、呼吸困难和肺炎。也有皮肤表现的报道，但很少有作者记录口腔的体征和症状。方法 报告3例确诊或疑似新型冠状病毒肺炎（COVID-19）患者出现口腔溃疡或水疱的病例。结果 1例患者血清学确诊为COVID-19，其余2例仅为疑似病例。2例患者报告腭部疼痛，第3例报告舌部疼痛。前2例患者的病变累及角化组织，与单纯疱疹病变一致，但无疱疹感染史。第3例患者的病变符合多形红斑。结论 作者认为COVID-19与口腔溃疡和水疱之间存在联系，但承认由于入院时缺乏口腔检查，这些体征可能常常未被发现。
