Division of Infectious Diseases, Department of Medicine, University of Pennsylvania Perelman School of Medicine, 3400 Spruce Street, Philadelphia, PA, 19104, USA.
Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
AIDS Behav. 2021 Jan;25(1):148-153. doi: 10.1007/s10461-020-02952-9.
Despite reductions in smoking rates in the general population, little is known about recent smoking trends among people living with HIV (PLWH). We compared the risk for smoking and temporal trends in smoking among PLWH and the general population in the Philadelphia metropolitan area between 2009 and 2014. We used weighted logistic regression to assess the relation between HIV and smoking, and examined temporal smoking trends. The adjusted odds ratio (OR) for smoking comparing PLWH to the general population was 1.80 (95% CI 1.55-2.09) after adjusting for socio-economic, demographic, and mental health diagnosis variables. Smoking prevalence decreased in both the PLWH and general populations during the study period, and we did not observe a significant difference in rates of decline between groups (P = 0.54). Despite overall progress in smoking cessation, a disparity persisted in smoking rates between PLWH and the general population, with and without adjustment for socio-economic, demographic, and mental health variables. Further research is needed to understand the mechanisms linking HIV and tobacco use in order to inform public health efforts to reduce smoking among PLWH.
尽管普通人群中的吸烟率有所下降，但对于 HIV 感染者（PLWH）最近的吸烟趋势知之甚少。我们比较了 2009 年至 2014 年间，费城大都市区 PLWH 和普通人群的吸烟风险和吸烟时间趋势。我们使用加权逻辑回归来评估 HIV 与吸烟之间的关系，并检查了吸烟时间趋势。在调整了社会经济、人口统计学和心理健康诊断变量后，PLWH 与普通人群相比，吸烟的调整后比值比（OR）为 1.80（95%CI 1.55-2.09）。在研究期间，PLWH 和普通人群的吸烟率均有所下降，但我们没有观察到两组之间下降速度的显著差异（P=0.54）。尽管在戒烟方面取得了总体进展，但 PLWH 和普通人群之间的吸烟率仍然存在差异，无论是否调整社会经济、人口统计学和心理健康变量。需要进一步研究了解 HIV 和烟草使用之间的联系机制，以便为减少 PLWH 吸烟的公共卫生工作提供信息。
