Department of Neurology, School of Medicine, University of South Carolina, Columbia, SC.
J Periodontol. 2020 Oct;91 Suppl 1:S35-S39. doi: 10.1002/JPER.20-0138. Epub 2020 Aug 19.
Multiple risk factors are associated with ischemic stroke. Here, we highlight studies indicating that periodontal disease significantly increases the risk of both primary ischemic stroke and subsequent cardiovascular events. Additionally, studies have shown an association between periodontal disease and multiple causes of ischemic stroke. Finally, we describe an ongoing clinical trial testing the benefit of periodontal disease treatment as a strategy to reduce risk for recurrent cardiovascular events in patients who have had recent ischemic stroke or transient ischemic attack. This article is mostly based on a presentation given in honor of Steven Offenbacher (1950 to 2018).
多种风险因素与缺血性脑卒中相关。在这里，我们重点介绍一些研究，这些研究表明牙周病显著增加了原发性缺血性脑卒中以及随后发生心血管事件的风险。此外，研究还表明牙周病与多种缺血性脑卒中病因之间存在关联。最后，我们描述了一项正在进行的临床试验，该试验旨在评估牙周病治疗是否可降低近期发生缺血性脑卒中或短暂性脑缺血发作患者的心血管事件复发风险，以此作为一种策略。本文主要基于纪念 Steven Offenbacher（1950 年至 2018 年）的演讲内容。
