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迟发性失明对颈性前庭诱发肌源性电位的影响。

Effect of late-onset blindness on cervical vestibular evoked myogenic potentials.

机构信息

Department of Audiology, School of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran.

Department of Audiology, School of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran; Musculoskeletal Rehabilitation Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

出版信息

Am J Otolaryngol. 2020 Sep-Oct;41(5):102575. doi: 10.1016/j.amjoto.2020.102575. Epub 2020 Jun 1.

Abstract

PURPOSE

Approximately 1.3 billion people worldwide have vision impairment. The aim of the present study was to investigate the influence of Late-Onset blindness on cervical vestibular evoked myogenic potentials (cVEMP) responses. Accordingly, this study was performed to investigate and compare the parameters of the cVEMP test in sighted and late-onset blind individuals.

MATERIALS AND METHOD

In this cross-sectional- comparative study, cVEMP was recorded by presenting a tone burst stimulus of 500 Hz with an intensity of 95 dBnHL in 20 sighted and 20 late-onset blind individuals aged between 18 and 30 years old.

RESULTS

cVEMP was observed in all the individuals (100%). The average latency of P and N, amplitude, amplitude ratio, and VEMP threshold did not differ significantly between the two groups (p > 0.05).

CONCLUSION

The findings of the study revealed that the formation of the neural pathway and reflex arch of cVEMP is similar between late-onset blind and sighted individuals. Thus, cVEMP can be a suitable test for assessing the vestibular function of late-onset blind people.

摘要

目的

全球约有 13 亿人视力受损。本研究旨在探讨迟发性失明对视神经前庭诱发肌源性电位(cVEMP)反应的影响。因此,本研究旨在调查和比较视力正常和迟发性失明个体 cVEMP 测试的参数。

材料和方法

在这项横断面比较研究中,通过在 20 名视力正常和 20 名年龄在 18 至 30 岁之间的迟发性失明个体中呈现强度为 95 dBnHL 的 500 Hz 短音刺激,记录 cVEMP。

结果

所有个体(100%)均观察到 cVEMP。两组间 P 和 N 的潜伏期、振幅、振幅比和 VEMP 阈值无显著差异(p > 0.05)。

结论

研究结果表明,迟发性失明个体和视力正常个体的 cVEMP 神经通路和反射弧的形成相似。因此,cVEMP 可作为评估迟发性失明者前庭功能的合适测试。

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