Department of Audiology, School of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran.
Department of Audiology, School of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran; Musculoskeletal Rehabilitation Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Am J Otolaryngol. 2020 Sep-Oct;41(5):102575. doi: 10.1016/j.amjoto.2020.102575. Epub 2020 Jun 1.
Approximately 1.3 billion people worldwide have vision impairment. The aim of the present study was to investigate the influence of Late-Onset blindness on cervical vestibular evoked myogenic potentials (cVEMP) responses. Accordingly, this study was performed to investigate and compare the parameters of the cVEMP test in sighted and late-onset blind individuals.
In this cross-sectional- comparative study, cVEMP was recorded by presenting a tone burst stimulus of 500 Hz with an intensity of 95 dBnHL in 20 sighted and 20 late-onset blind individuals aged between 18 and 30 years old.
cVEMP was observed in all the individuals (100%). The average latency of P and N, amplitude, amplitude ratio, and VEMP threshold did not differ significantly between the two groups (p > 0.05).
The findings of the study revealed that the formation of the neural pathway and reflex arch of cVEMP is similar between late-onset blind and sighted individuals. Thus, cVEMP can be a suitable test for assessing the vestibular function of late-onset blind people.
全球约有 13 亿人视力受损。本研究旨在探讨迟发性失明对视神经前庭诱发肌源性电位（cVEMP）反应的影响。因此，本研究旨在调查和比较视力正常和迟发性失明个体 cVEMP 测试的参数。
在这项横断面比较研究中，通过在 20 名视力正常和 20 名年龄在 18 至 30 岁之间的迟发性失明个体中呈现强度为 95 dBnHL 的 500 Hz 短音刺激，记录 cVEMP。
所有个体（100%）均观察到 cVEMP。两组间 P 和 N 的潜伏期、振幅、振幅比和 VEMP 阈值无显著差异（p > 0.05）。
研究结果表明，迟发性失明个体和视力正常个体的 cVEMP 神经通路和反射弧的形成相似。因此，cVEMP 可作为评估迟发性失明者前庭功能的合适测试。
