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肥胖患者行袖状胃切除术联合食管裂孔疝修补术:胃食管反流病的长期疗效。

Sleeve gastrectomy with concomitant hiatal hernia repair in obese patients: long-term results on gastroesophageal reflux disease.

机构信息

Department of Public Health, "Federico II" University, Naples, Italy.

Department of Medicine, Surgery and Dentistry, "Scuola Medica Salernitana," University of Salerno, Salerno, Italy.

出版信息

Surg Obes Relat Dis. 2020 Sep;16(9):1171-1177. doi: 10.1016/j.soard.2020.04.049. Epub 2020 May 11.

Abstract

BACKGROUND

Hiatal hernia repair (HHR) during Sleeve Gastrectomy (SG) is recommended when the defect is intraoperatively found; however, the long term effect on gastro-esophageal reflux disease (GERD) remains controversial.

OBJECTIVES

This study aimed to report long-term follow-up data, at least after 7 years, of SG with concomitant HHR and the outcome on GERD symptoms.

SETTING

Tertiary-care referral hospital.

METHODS

This study retrospectively analyzed 91 obese patients submitted to SG + HHR with a minimum of 7-years follow-up. The preoperative evaluation included GERD symptoms assessment by a standardized questionnaire, proton pump inhibitor usage evaluation, an upper gastrointestinal endoscopy, and a barium-swallow esophagogram to detect the presence of HH. At long-term follow-up visit, GERD assessment was performed to evaluate remission, persistence, or new onset of typical GERD symptoms; proton pump inhibitor usage was also investigated. Patients underwent barium-swallow esophagogram and/or upper gastrointestinal endoscopy.

RESULTS

At long-term evaluation, 2 of 91 patients (2.2%) were lost and 1 patient underwent Roux-en-Y gastric bypass. Of patients with preoperative GERD, 60% had GERD resolution; however, 27 of 88 (30.6%) patients reported postoperative GERD symptoms. Among these patients 15 (55.5%) showed the HH recurrence detected by barium-swallow esophagogram. All patients with HH recurrence had esophagitis and 1 case had a Barrett's esophagus. In the remaining 12 patients (44.4%) with postoperative GERD without HH recurrence, the barium-swallow esophagogram showed signs of reflux in reverse Trendelenburg.

CONCLUSIONS

At long-term follow-up HH recurrence was consistently related to the presence of GERD symptoms and to a high rate of esophagitis and Barrett's esophagus. In all patients with GERD symptoms after SG + HHR, a HH recurrence should be suspected and an upper gastrointestinal endoscopy strongly recommended to rule out esophagitis, and especially Barrett's esophagus.

摘要

背景

食管裂孔疝修复(HHR)在袖状胃切除术(SG)中被推荐用于术中发现的缺陷;然而,其对胃食管反流病(GERD)的长期影响仍存在争议。

目的

本研究旨在报告 SG 合并 HHR 的长期随访数据,至少随访 7 年以上,以及对 GERD 症状的结果。

设置

三级转诊医院。

方法

本研究回顾性分析了 91 例接受 SG+HHR 治疗且随访时间至少 7 年的肥胖患者。术前评估包括 GERD 症状的标准化问卷评估、质子泵抑制剂使用评估、上消化道内窥镜检查和钡剂吞咽食管造影以检测 HH 的存在。在长期随访时,评估 GERD 以评估典型 GERD 症状的缓解、持续或新发;还调查了质子泵抑制剂的使用情况。患者接受了钡剂吞咽食管造影和/或上消化道内窥镜检查。

结果

在长期评估中,91 例患者中有 2 例(2.2%)丢失,1 例患者接受了 Roux-en-Y 胃旁路术。在术前有 GERD 的患者中,60%的患者 GERD 得到缓解;然而,88 例患者中有 27 例(30.6%)报告术后 GERD 症状。在这些患者中,15 例(55.5%)出现了钡剂吞咽食管造影检测到的 HH 复发。所有 HH 复发的患者均有食管炎,1 例有 Barrett 食管。在其余 12 例(44.4%)术后 GERD 且无 HH 复发的患者中,钡剂吞咽食管造影显示反向 Trendelenburg 反流迹象。

结论

在长期随访中,HH 复发与 GERD 症状的存在以及食管炎和 Barrett 食管的高发生率密切相关。在所有接受 SG+HHR 后出现 GERD 症状的患者中,应怀疑 HH 复发,并强烈建议进行上消化道内窥镜检查以排除食管炎,尤其是 Barrett 食管。

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