Mazzola F, Tomasoni M, Mocellin D, Dalè M, Iandelli A, Carobbio A, Marchi F, Filauro M, Petruzzi G, Massa B, Facchetti M, Battocchio S, Marandino F, Lombardi D, Pichi B, Pellini R, Nicolai P, Peretti G
Unit of Otorhinolaryngology and Head and Neck Surgery, IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, 10, 16132, Genoa, Italy; Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Viale Benedetto XV, 6, 16132, Genoa, Italy; Department of Otolaryngology - Head and Neck Surgery, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi, 53, 00144, Rome, Italy.
Unit of Otorhinolaryngology, Head and Neck Surgery, Department of Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Piazzale Spedali Civili, 1 - 25123, Brescia, Italy.
Oral Oncol. 2020 Jun 25;109:104867. doi: 10.1016/j.oraloncology.2020.104867.
Fine-needle aspiration cytology (FNAC) is a basic step in the diagnosis of salivary gland tumors that have a wide variety of histological types. The recent Milan system for reporting salivary gland cytopathology (MSRSGC) can correlate the risk of malignancy with precise cytological features. A revised version was recently proposed to improve the surgical relevance and facilitate uniform management.
A multicenter study retrospectively used the original and revised MSRSGC criteria to classify a series of patients who received surgery after FNAC.
We enrolled 503 patients from three tertiary centers. The risk of malignancy for the MSRSGC resulted 19.5% in cat. I, 14.3% in cat. II, 17.6% in cat. III, 3.6% in cat. IVa, 24.6% in cat. IVb, 66.7% in cat. V, and 96.8% in cat. VI. The results from the revised MSRSGC were consistent with the original values.
The MSRSGC is a promising classification system. In our opinion, the revised version of the MSRSGC supplements FNAC with some crucial clinical information and can better identify the appropriate treatment in each category.
细针穿刺细胞学检查(FNAC)是诊断具有多种组织学类型的涎腺肿瘤的基本步骤。最近的涎腺细胞病理学报告米兰系统(MSRSGC)能够将恶性风险与精确的细胞学特征相关联。最近提出了一个修订版以提高手术相关性并促进统一管理。
一项多中心研究回顾性地使用原始版和修订版MSRSGC标准对一系列在FNAC后接受手术的患者进行分类。
我们纳入了来自三个三级中心的503例患者。MSRSGC的恶性风险在I类为19.5%,II类为14.3%,III类为17.6%,IVa类为3.6%,IVb类为24.6%,V类为66.7%,VI类为96.8%。修订版MSRSGC的结果与原始值一致。
MSRSGC是一个有前景的分类系统。我们认为,MSRSGC的修订版为FNAC补充了一些关键的临床信息,并且能够更好地确定每一类别的合适治疗方法。