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苏门答腊野生芒果( spp.)的植物化学成分筛查和抗氧化分析:一种具有潜在医学抗退行性作用的药物来源。

Phytochemical screening and antioxidant profiling of Sumatran wild mangoes ( spp.): a potential source for medicine antidegenerative effects.

机构信息

Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Riau, Pekanbaru, Riau, 28293, Indonesia.

Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Riau, Pekanbaru, Riau, 28293, Indonesia.

出版信息

F1000Res. 2020 Mar 31;9:220. doi: 10.12688/f1000research.22380.3. eCollection 2020.

Abstract

New findings on the potential of wild mangoes from the island of Sumatra as a source of antioxidant helps their conservation effort as it introduces their useful compounds to the public. This study aims to analyze the antioxidant profile and quantification of gallic acid and quercetin content from leaves and bark of Sumatran wild mangoes. Exploration and analysis of phytochemical constituents from 11 Sumatran wild mangoes was performed. Antioxidant activity of wild mangoes was analysed with 1,1- diphenyl-2-picryl hydroxyl (DPPH), and determination of quercetin and gallic acid content was performed by high performance liquid chromatography (HPLC) method. Total flavonoid and phenolic analysis was also performed. Curve fitting analysis used a linear regression approach. The highest level of antioxidant activity, phenolic compound and flavonoid compound was found in the leaves and bark of sp1. (MBS), the bark of (var. batu) and leaves of , and the bark and leaves of , respectively. The content of gallic acid in leaves ranged from 5.23-35.48 mg/g dry weight. Quercetin content of wild mangoes leaves ranged from 0.76 to 1.16 mg/g dry weight with the lowest value in (var. manis) and the highest in . The results obtained are expected to be useful in supporting the development of drugs that have antidegenerative effects.

摘要

新发现苏门答腊岛野生芒果具有抗氧化潜力,有助于保护它们,因为这将向公众介绍它们有用的化合物。本研究旨在分析苏门答腊野生芒果叶和树皮的抗氧化特性和没食子酸、槲皮素含量的定量分析。对 11 种苏门答腊野生芒果进行了植物化学成分的探索和分析。采用 1,1-二苯基-2-苦基肼基(DPPH)分析野生芒果的抗氧化活性,采用高效液相色谱(HPLC)法测定槲皮素和没食子酸含量。还进行了总类黄酮和总酚分析。曲线拟合分析采用线性回归方法。在 sp1 的叶和树皮(MBS)、(var. batu)的树皮和 的叶、 的树皮和叶中发现了最高水平的抗氧化活性、酚类化合物和类黄酮化合物。叶中没食子酸的含量范围为 5.23-35.48 mg/g 干重。野生芒果叶中槲皮素的含量范围为 0.76 至 1.16 mg/g 干重, 值最低的是 (var. manis), 值最高的是 。预计所获得的结果将有助于开发具有抗退行性作用的药物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bf2/7327720/18fea5c4917a/f1000research-9-27684-g0000.jpg

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