Leemans Maartje, van Sluis Klaske E, van Son Rob J J H, van den Brekel Michiel W M
Department of Head and Neck Oncology and Surgery Netherlands Cancer Institute-Antoni van Leeuwenhoek Amsterdam The Netherlands.
Amsterdam Center for Language and Communication University of Amsterdam Amsterdam The Netherlands.
Laryngoscope Investig Otolaryngol. 2020 Apr 15;5(3):453-460. doi: 10.1002/lio2.381. eCollection 2020 Jun.
Total laryngectomy (TL) leads to lifelong physical changes which can lead to functional and participation issues. To assess the relationship between self-reported quality of life and functional and participation issues, a large international online questionnaire was used.
A questionnaire was sent out to 8119 recipients of whom 1705 (21%) responded. The questionnaire consisted of 26 questions regarding demographic information, product use of the respondents, experienced overall health and independence, and functional and participation issues. Respondents were grouped based on sex, age, time since TL, educational level, and country of residence. Questions were grouped in one measure of reported quality of life (r-QoL) and seven issue themes ("esthetic issues," "experienced limitations in daily activities," "avoiding social activities," "communication issues," "experienced vulnerability due to environmental factors," "pulmonary issues," and "sleep issues") to assess the underlying relations.
This study showed that more functional and participation issues and a lower r-QoL are reported in the group of younger respondents (<60 years), women, and respondents who have had the TL procedure less than 2 years ago. The issue themes "experienced limitations in daily activities" and "avoiding social activities" are related to r-QoL. Most participants report "pulmonary issues," and these issues have a strong correlation with most other themes.
The ability to participate in meaningful and social activities is a major factor in r-QoL. Due to the frequency and strong correlations of pulmonary issues with other issue themes, pulmonary issues might be an underlying cause of many other issues.
3b.
全喉切除术（TL）会导致终身身体变化，进而引发功能和参与方面的问题。为评估自我报告的生活质量与功能和参与问题之间的关系，我们使用了一份大型国际在线调查问卷。
向8119名受访者发放了问卷，其中1705人（21%）做出了回应。问卷包含26个问题，涉及人口统计学信息、受访者的产品使用情况、总体健康和独立体验以及功能和参与问题。受访者根据性别、年龄、全喉切除术后时间、教育水平和居住国家进行分组。问题被归为一项自我报告的生活质量指标（r-QoL）和七个问题主题（“美学问题”“日常活动中的体验限制”“避免社交活动”“沟通问题”“因环境因素而体验到的脆弱性”“肺部问题”和“睡眠问题”），以评估潜在关系。
本研究表明，在年轻受访者（<60岁）、女性以及全喉切除手术时间不到2年的受访者群体中，报告的功能和参与问题更多，r-QoL更低。“日常活动中的体验限制”和“避免社交活动”这两个问题主题与r-QoL相关。大多数参与者报告了“肺部问题”，并且这些问题与大多数其他主题有很强的相关性。
参与有意义的社交活动的能力是r-QoL的一个主要因素。由于肺部问题与其他问题主题的频率和强相关性，肺部问题可能是许多其他问题的潜在原因。
3b。
