College of Natural & Applied Sciences, University of Guam, Mangilao, Guam (GB).
Cancer Research Center, University of Guam, Mangilao, Guam (BS, RB, RTLG).
Hawaii J Health Soc Welf. 2020 Jun 1;79(6 Suppl 2):40-44.
Breast cancer is the second leading cause of cancer-related death among women on Guam and Hawai'i. Breast cancer incidence rates are described here for the multiethnic population in Guam, a United States (US) Pacific island territory, and compared to Hawai'i and other US populations, to understand the risk by age and race/ethnic group in this understudied group. The study included all breast cancer cases (n=576) reported to the Guam Cancer Registry, all breast cancer cases (n=8345) reported to the Hawai'i Tumor Registry and all breast cancer cases (n=678,637) reported to the Surveillance, Epidemiology, and End Results program from 2000 to 2009. Cumulative incidence rates by age were calculated for two time periods: 2000-2004 and 2005-2009. Differences were seen in cumulative incidence rates by age, ethnicity, and place of residence. Cumulative incidence rates by age 40 were the highest (0.7%) among Filipinos in Guam but, after age 40, the rates for Chamorros (indigenous Pacific Islanders of Guam) increased rapidly. The lifetime cumulative incidence rates were the highest for Chamorros in Guam (15.3%), close to the US rate (15.5%). Results were similar for 2005-2009. Women in Guam are at high risk for breast cancer, with the indigenous Chamorros having the highest risk, and the most prevalent Asian group of Filipinos, having a younger age at diagnosis. These patterns are similar to the comparable Pacific Islander and Filipino populations in Hawai'i and the US generally.
乳腺癌是关岛和夏威夷女性癌症相关死亡的第二大主要原因。本研究描述了关岛多民族人群的乳腺癌发病率，并与夏威夷和其他美国人群进行了比较，以了解该研究人群中按年龄和种族/族裔划分的风险。本研究包括 2000 年至 2009 年向关岛癌症登记处报告的所有乳腺癌病例（n=576）、向夏威夷肿瘤登记处报告的所有乳腺癌病例（n=8345）和向监测、流行病学和结果计划报告的所有乳腺癌病例（n=678637）。按年龄计算了两个时期（2000-2004 年和 2005-2009 年）的累积发病率。年龄、族裔和居住地的累积发病率存在差异。关岛菲律宾人 40 岁时的累积发病率最高（0.7%），但 40 岁后，关岛查莫罗人（关岛的土著太平洋岛民）的发病率迅速上升。关岛查莫罗人的终身累积发病率最高（15.3%），接近美国的发病率（15.5%）。2005-2009 年的结果相似。关岛女性患乳腺癌的风险很高，其中土著查莫罗人风险最高，最常见的亚洲群体菲律宾人，诊断年龄更小。这些模式与夏威夷和美国一般可比的太平洋岛民和菲律宾人群相似。
