Wimalawansa S J, Macintyre I
Department of Chemical Pathology, Royal Postgraduate Medical School, London, UK.
Peptides. 1988 Mar-Apr;9(2):407-10. doi: 10.1016/0196-9781(88)90276-8.
Calcitonin gene-related peptide (CGRP) in plasma is heterogeneous and derived from both neural tissues and from the thyroid gland in the rat. CGRP is widely distributed in neural and cardiovascular tissues, and also in the thyroid gland in rat. We have previously shown that the main source of circulatory CGRP is the perivascular nerves. The present study shows that, in addition to the neural tissues, the thyroid gland may also contribute to the circulating pool of immunoreactive-CGRP.
血浆中的降钙素基因相关肽（CGRP）具有异质性，在大鼠中它既来源于神经组织，也来源于甲状腺。CGRP广泛分布于神经和心血管组织，在大鼠的甲状腺中也有分布。我们之前已经表明，循环CGRP的主要来源是血管周围神经。本研究表明，除神经组织外，甲状腺也可能对免疫反应性CGRP的循环池有贡献。
