Nephrology and Kidney Transplantation Department, Centro Hospitalar e Universitário do Porto, Porto, Portugal.
Infectious Diseases Department, Centro Hospitalar e Universitário do Porto, Porto, Portugal.
Transpl Infect Dis. 2021 Feb;23(1):e13394. doi: 10.1111/tid.13394. Epub 2020 Jul 14.
From December 2019 to March 2020, China was the epicenter of the SARS-CoV-2 infection pandemic, but from that moment on, Europe surpassed China in the number of new cases and deaths related to this novel viral respiratory infection. The emergence of this world pandemic is particularly important for solid organ transplant recipients, who might have an increased risk of mortality, not only due to their chronic immunosuppression status, but also to the cardiovascular risk that correlates with several years of chronic kidney disease. To the extent that there is still a lack of knowledge about the clinical characteristics, evolution, and prognosis of SARS-CoV-2 infection in kidney transplant recipients, we will report the first 5 cases diagnosed and followed in our transplant unit, as well as share the therapeutic strategies adopted.
从 2019 年 12 月到 2020 年 3 月，中国是 SARS-CoV-2 感染大流行的中心，但从那时起，欧洲在与这种新型病毒性呼吸道感染相关的新发病例和死亡人数上超过了中国。这场世界性大流行对实体器官移植受者来说尤为重要，他们的死亡率可能会增加，这不仅是因为他们处于慢性免疫抑制状态，还因为与慢性肾病相关的心血管风险。在一定程度上，我们对肾移植受者 SARS-CoV-2 感染的临床特征、演变和预后仍然缺乏了解，因此我们将报告在我们的移植单位诊断和随访的前 5 例病例，并分享所采用的治疗策略。
