Taneja Saumya, Singh Abinav
Gen Dent. 2020 Jul-Aug;68(4):50-55.
Despite the worldwide decline in dental caries, pit and fissure caries remains a cause of concern, and application of pit and fissure sealants is an important preventive measure. Due to the high wear rate of conventional unfilled sealants, various other materials have been tested for fissure sealing. The present meta-analysis was conducted to compare the effectiveness of flowable composite resins as a fissure sealant to that of conventional pit and fissure sealants. A literature search was performed in MEDLINE, Cochrane Database of Systematic Reviews, and Google Scholar. Clinical trials comparing the efficacy of flowable composite resins as fissure sealants to that of conventional pit and fissure sealants on permanent teeth with a follow-up of 12 or 24 months were included in this meta-analysis. The retention rates of the 2 groups were evaluated with a random-effects model using Cochrane Reviews software (Cochrane RevMan, version 5.3). Seven studies were included in the final review. Flowable composite resins proved to be a significantly better fissure-sealing material after 1 year of follow-up (odds ratio = 0.47; 95% CI = 0.22-1.01; P = 0.05; degree of inconsistency [I] = 59%). The retention rates of flowable composite resins at the end of 2 years were similar to those of conventional pit and fissure sealants (odds ratio = 0.71; 95% CI = 0.13-3.95; P = 0.70; I = 85%). Flowable composite resins proved to be a superior alternative to conventional sealants after 1 year of follow-up; however, no such difference between the 2 groups was observed after 2 years of follow-up. Further longitudinal studies should be conducted to evaluate the long-term retention and efficacy of flowable composite resins in fissure sealing.
尽管全球龋齿发病率呈下降趋势,但窝沟龋仍然令人担忧,应用窝沟封闭剂是一项重要的预防措施。由于传统非填充型封闭剂磨损率高,人们对多种其他材料进行了窝沟封闭测试。本荟萃分析旨在比较可流动复合树脂作为窝沟封闭剂与传统窝沟封闭剂的有效性。我们在医学文献数据库(MEDLINE)、考克兰系统评价数据库和谷歌学术进行了文献检索。本荟萃分析纳入了比较可流动复合树脂作为窝沟封闭剂与传统窝沟封闭剂对恒牙疗效且随访12个月或24个月的临床试验。使用考克兰评价软件(Cochrane RevMan,5.3版)的随机效应模型评估两组的保留率。最终综述纳入了七项研究。随访1年后,可流动复合树脂被证明是一种明显更好的窝沟封闭材料(优势比=0.47;95%置信区间=0.22-1.01;P=0.05;不一致程度[I]=59%)。2年后可流动复合树脂的保留率与传统窝沟封闭剂相似(优势比=0.71;95%置信区间=0.13-3.95;P=0.70;I=85%)。随访1年后,可流动复合树脂被证明是优于传统封闭剂的替代品;然而,随访2年后未观察到两组之间存在此类差异。应开展进一步的纵向研究,以评估可流动复合树脂在窝沟封闭中的长期保留率和疗效。