Department of Electronics & Communication Engineering, Annamalai University, Annamalai Nagar, Tamilnadu- 608002, India.
Department of Bio Medical Engineering, Saveetha School of Engineering, Saveetha University, Thandalam, Tamilnadu-602105, India.
Curr Med Imaging. 2021;17(3):319-330. doi: 10.2174/1573405616666200628134800.
The aim was to study image fusion-based cancer classification models used to diagnose cancer and assess medical problems in earlier stages that help doctors or health care professionals to make the treatment plan accordingly.
In this work, a novel image fusion method based on Curvelet transform is developed. CT and PET scan images of benign type tumors were fused together using the proposed fusion algorithm and the same way, MRI and PET scan images of malignant type tumors were fused together to achieve the combined benefits of individual imaging techniques. Then, the marker-controlled watershed algorithm was applied on fused images to segment cancer affected area. The various color features, shape features and texture-based features were extracted from the segmented image. Following this, a data set was formed with various features, given as input to different classifiers namely neural network classifier, Random forest classifier, and K-NN classifier to determine the nature of cancer. The results of the classifier showed normal, benign or malignant category of cancer.
The performance of the proposed fusion algorithm was compared with the existing fusion techniques based on the parameters PSNR, SSIM, Entropy, Mean and Standard Deviation. Curvelet transform based fusion method performs better than already existing methods in terms of five parameters. The performances of the classifiers were evaluated using three parameters: accuracy, sensitivity, and specificity. The K-NN Classifier performed better compared to the other two classifiers and it provided an overall accuracy of 94%, sensitivity of 88% and specificity of 84%.
The proposed Curvelet transform based image fusion method combined with the KNN classifier provides better results compared to other two classifiers when two input images were used individually.
本研究旨在探讨基于图像融合的癌症分类模型,该模型用于诊断癌症,并在更早阶段评估医疗问题,以帮助医生或医疗保健专业人员制定相应的治疗计划。
在这项工作中,提出了一种基于 Curvelet 变换的新的图像融合方法。使用所提出的融合算法将良性肿瘤的 CT 和 PET 扫描图像融合在一起,同样地,将恶性肿瘤的 MRI 和 PET 扫描图像融合在一起,以实现各个成像技术的综合优势。然后,将标记控制分水岭算法应用于融合图像以分割癌症受影响的区域。从分割后的图像中提取各种颜色特征、形状特征和基于纹理的特征。接下来,将各种特征形成一个数据集,作为输入提供给不同的分类器,即神经网络分类器、随机森林分类器和 K-NN 分类器,以确定癌症的性质。分类器的结果显示为正常、良性或恶性癌症类别。
将所提出的融合算法的性能与基于 PSNR、SSIM、熵、均值和标准差的现有融合技术进行了比较。基于 Curvelet 变换的融合方法在五个参数方面优于现有的方法。使用三个参数评估了分类器的性能:准确性、敏感性和特异性。与其他两个分类器相比,K-NN 分类器表现更好,其总体准确率为 94%,敏感性为 88%,特异性为 84%。
与单独使用两个输入图像的其他两种分类器相比,所提出的基于 Curvelet 变换的图像融合方法与 KNN 分类器结合使用可以提供更好的结果。