Institute of Fluid Mechanics, Karlsruhe Institute of Technology, Karlsruhe, Germany.
Biomed Tech (Berl). 2020 Oct 25;65(5):595-603. doi: 10.1515/bmt-2019-0175.
Tools for the numerical prediction of haemodynamics in multi-disciplinary integrated heart simulations have to be based on computational models that can be solved with low computational effort and still provide physiological flow characteristics. In this context the mitral valve model is important since it strongly influences the flow kinematics, especially during the diastolic phase. In contrast to a 3D valve, a vastly simplified valve model in form of a simple diode is known to be unable to reproduce the characteristic vortex formation and unable to promote a proper ventricular washout. In the present study, an adaptation of the widely used simplest modelling approach for the mitral valve is employed and compared to a physiologically inspired 3D valve within the same ventricular geometry. The adapted approach shows enhanced vortex formation and an improved ventricular washout in comparison to the diode type model. It further shows a high potential in reproducing the main flow characteristics and related particle residence times generated by a 3D valve.
用于多学科综合心脏模拟中血液动力学数值预测的工具必须基于能够以低计算成本解决的计算模型，并且仍然能够提供生理流动特性。在这方面，二尖瓣模型很重要，因为它强烈影响流动运动学，特别是在舒张期。与 3D 瓣膜相比，众所周知，简化形式的简单二极管瓣膜模型无法再现特征性的涡旋形成，也无法促进适当的心室冲洗。在本研究中，采用了广泛使用的二尖瓣最简单建模方法的一种改编，并与相同心室几何形状内的生理启发 3D 瓣膜进行了比较。与二极管模型相比，改编后的方法显示出增强的涡旋形成和改善的心室冲洗。它还显示出在再现由 3D 瓣膜产生的主流特性和相关粒子停留时间方面具有很高的潜力。
