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[血管内超声检查对冠心病患者的诊断意义]

[Diagnostic significance of angioscopy in patients with coronary heart disease].

作者信息

Höher M, Hombach V, Höpp H W, Eggeling T, Kochs M, Arnold G, Hannekum A, Hügel W

机构信息

Medizinische Klinik III, Universität Köln.

出版信息

Z Kardiol. 1988 Mar;77(3):152-9.

PMID:3260058
Abstract

Coronary angioscopy (CA) using ultrathin fiberscopes was performed in 30 patients with coronary heart disease during cardiac catheterization and in 11 patients during bypass surgery. For percutaneous CA the angioscope was introduced from the femoral artery through a 9F guiding catheter. During short-time occlusion of the coronary ostium by the tip of the guiding catheter the viewing field was flushed with Ringer's solution. Intraoperative CA was performed both by the retrograde and antegrade way during flushing with cardioplegic solution. Percutaneous CA was successful in 57% of patients. 13 patients showed eccentrically and irregularly shaped stenoses and 3 of these patients had an additional plaque rupture. In 2/5 patients CA after PTCA revealed intimal dissections not visualized by angiography. Intraoperative CA was successful in 9/11 patients. In 3 patients nonocclusive thrombi were found at the site of the coronary lesion. Additionally we studied the efficacy of angioscopic guidance during intravascular radiofrequency application. In 11/11 thrombotically occluded peripheral vessels this new method allowed a nearly complete recanalization. There was only one perforation of the vessel. We conclude, that CA is a powerful diagnostic tool providing prognostically relevant information in the diagnosis of coronary heart disease.

摘要

30例冠心病患者在心脏导管插入术期间以及11例患者在搭桥手术期间,使用超薄纤维内镜进行了冠状动脉血管镜检查(CA)。对于经皮CA,血管镜通过一根9F引导导管从股动脉插入。在引导导管尖端短暂阻塞冠状动脉口期间,视野用林格氏液冲洗。术中CA在使用心脏停搏液冲洗期间通过逆行和顺行方式进行。经皮CA在57%的患者中成功。13例患者显示出偏心且形状不规则的狭窄,其中3例患者还有额外的斑块破裂。在2/5的患者中,PTCA后的CA显示出血管造影未发现的内膜撕裂。术中CA在9/11的患者中成功。在3例患者的冠状动脉病变部位发现了非闭塞性血栓。此外,我们研究了血管镜引导在血管内射频应用中的效果。在11/11例血栓闭塞性外周血管中,这种新方法实现了几乎完全再通。仅发生了1例血管穿孔。我们得出结论,CA是一种强大的诊断工具,在冠心病诊断中可提供与预后相关的信息。

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