Babb R R, Mitchell R L
Palo Alto Medical Clinic, California.
Am J Gastroenterol. 1988 Jul;83(7):777-9.
Our patient, with cirrhosis, portal hypertension, varices, and chronic gastrointestinal bleeding from hemorrhagic gastritis, illustrates an important therapeutic principle. Since the gastritis is related to vascular changes and congestion of the stomach wall secondary to increased portal pressure, and not inflammation, measures aimed at local healing or surgical removal of the bleeding area fail. One must attempt to lower portal pressure with drugs such as propranolol and/or undertake portal decompressive surgery.
我们的这位患有肝硬化、门静脉高压、静脉曲张以及因出血性胃炎导致慢性胃肠道出血的患者,阐释了一条重要的治疗原则。由于胃炎与门静脉压力升高继发的胃壁血管变化和充血有关,而非炎症,旨在局部愈合或手术切除出血区域的措施均告失败。必须尝试使用普萘洛尔等药物降低门静脉压力,和/或进行门静脉减压手术。