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患者报告结局指标在胰腺癌患者中的潜在应用,特别关注老年患者。

The potential use for patient reported outcome measures in people with pancreatic cancer, with a specific focus on older patients.

机构信息

Pancreatic Cancer UK, 4th Floor Westminster Tower, 3 Albert Embankment, London, SE1 7SP, UK.

Pancreatic Cancer UK, 4th Floor Westminster Tower, 3 Albert Embankment, London, SE1 7SP, UK.

出版信息

Eur J Surg Oncol. 2021 Mar;47(3 Pt A):495-502. doi: 10.1016/j.ejso.2020.05.010. Epub 2020 May 20.

Abstract

Pancreatic cancer is one of the most lethal malignancies and is characterised by high-unmet physical and psychological supportive care needs. Patient Reported Outcome Measures (PROMs) represent a patient centred approach to address the high unmet supportive care need and improve the quality of care. PROMs have the potential to inform patients about the quality of life and symptom trajectory for different treatment approaches so that they can fully participate in shared decisions about treatment. Embedding the collection of PROMs into routine practice alongside clinical alerts and directed symptom interventions is acceptable and feasible for people with pancreatic cancer and has the potential to reduce symptom burden. There is also limited information on survival, quality of life and the holistic impact of treatment for older pancreatic cancer patients, therefore, PROMs provide an opportunity to understand the impact of treatment on older patients and better inform shared treatment decision-making.

摘要

胰腺癌是最致命的恶性肿瘤之一,其特点是身体和心理支持性护理需求未得到满足。患者报告的结局测量(PROMs)代表了以患者为中心的方法,以解决高未满足的支持性护理需求并提高护理质量。PROMs 有可能告知患者不同治疗方法的生活质量和症状轨迹,以便他们能够充分参与关于治疗的共同决策。将 PROMs 的收集与临床警报和定向症状干预一起纳入常规实践是可以接受且可行的,适用于胰腺癌患者,并有可能减轻症状负担。关于老年胰腺癌患者的生存、生活质量和治疗的整体影响的信息也很有限,因此,PROMs 提供了一个了解治疗对老年患者的影响并更好地为共同治疗决策提供信息的机会。

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