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为什么要关注老年结直肠癌患者的患者报告结局测量?

Why focus on patient-reported outcome measures in older colorectal cancer patients?

机构信息

Beth Israel Deaconess Medical Center, 330 Brookline Ave., Deaconess 306, Boston, MA, 02215, USA.

Boston Medical Center, One Boston Medical Center Place, Boston, MA, 02118, USA.

出版信息

Eur J Surg Oncol. 2020 Mar;46(3):394-401. doi: 10.1016/j.ejso.2019.07.028. Epub 2019 Jul 25.

DOI:10.1016/j.ejso.2019.07.028
PMID:31377032
Abstract

Colorectal cancer is the most common cancer among older persons, with surgery the recommended treatment for many. With a growing emphasis on value-based care, there is an increasing desire to implement patient-reported outcome measures. Patient-reported outcome measures (PROMs) are the tools and instruments used to collect patient-reported symptoms, functional status, and quality of life. Monitoring and addressing PROMs has been shown to improve patient-centered care in surgical oncology populations and survival in patients with advanced cancer. For older patients, functional status and quality of life are valuable outcomes of cancer treatment. However, experience with PROMs for older patients, and specifically older colorectal cancer patients, is limited and heterogenous. The International Consortium for Health Outcomes Measurement has recommended a set of outcome measures for colorectal cancer patients and a set of outcome measures for older patients, which have considerable overlap, providing a starting point for future investigations of PROMs for older colorectal cancer patients. While many questions remain, it is imperative that PROMs for older colorectal cancer patients be considered for their potential to improve cancer outcomes in this population.

摘要

结直肠癌是老年人中最常见的癌症,许多患者推荐采用手术治疗。随着对基于价值的护理的日益重视,人们越来越希望实施患者报告的结果测量。患者报告的结果测量(PROMs)是用于收集患者报告的症状、功能状态和生活质量的工具和仪器。监测和解决 PROMs 已被证明可以改善外科肿瘤患者的以患者为中心的护理和晚期癌症患者的生存。对于老年患者,功能状态和生活质量是癌症治疗的有价值的结果。然而,针对老年患者,特别是老年结直肠癌患者的 PROMs 经验有限且存在异质性。国际健康结果测量联合会已为结直肠癌患者推荐了一组结果测量指标,以及一组针对老年患者的结果测量指标,它们有很大的重叠,为未来针对老年结直肠癌患者的 PROMs 研究提供了起点。尽管仍有许多问题悬而未决,但考虑到老年结直肠癌患者的 PROMs 有改善该人群癌症结局的潜力,这一点至关重要。

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