Ryan Kimberley, Greenslade Jaimi, Williams Julian
Emergency and Trauma Centre, Royal Brisbane and Women's Hospital, Herston, Queensland, Australia.
Faculty of Health, School of Nursing, Queensland University of Technology, Brisbane, Queensland, Australia.
Emerg Med Australas. 2020 Dec;32(6):1008-1014. doi: 10.1111/1742-6723.13552. Epub 2020 Jun 29.
Early recognition and treatment for sepsis is critical in improving patient outcomes. The present study sought to examine whether triage location was associated with time to appropriate antibiotics in a cohort of ED patients with septic shock.
Septic shock patients were identified from a database of ED patients admitted with infection. Demographic, clinical and outcome data were reported by triage location. Time to event analyses sought to identify the association between triage location and time to appropriate antibiotic. Secondary outcome variables included ED and hospital length of stay (LOS), 30-day mortality, and ICU admission.
Time to appropriate antibiotic administration was longer for those patients triaged to lower acuity (242 min) compared to higher acuity (98 min, P < 0.01) locations. After adjustment for severity of illness, hospital LOS, ED LOS and 30-day mortality were similar regardless of the triaged location. Admission to ICU was lower for patients triaged to lower (7.3%) compared to higher (47.3%) acuity treatment locations.
We identified a sub-group of septic shock patients triaged to a lower acuity treatment location who received significant delays to antibiotics. This research area deserves closer examination to potentially recognise septic shock earlier in the continuum.
早期识别和治疗脓毒症对于改善患者预后至关重要。本研究旨在探讨在一组感染性休克的急诊科(ED)患者中,分诊地点是否与使用合适抗生素的时间相关。
从因感染入院的急诊科患者数据库中识别出感染性休克患者。按分诊地点报告人口统计学、临床和结局数据。事件发生时间分析旨在确定分诊地点与使用合适抗生素时间之间的关联。次要结局变量包括急诊科和住院时间(LOS)、30天死亡率和重症监护病房(ICU)入住情况。
与分诊至较高 acuity(98分钟,P < 0.01)地点的患者相比,分诊至较低 acuity(242分钟)的患者使用合适抗生素的时间更长。在对疾病严重程度进行调整后,无论分诊地点如何,住院时间、急诊科住院时间和30天死亡率均相似。分诊至较低 acuity(7.3%)治疗地点的患者入住ICU的比例低于分诊至较高 acuity(47.3%)治疗地点的患者。
我们识别出一组分诊至较低 acuity 治疗地点的感染性休克患者,他们在使用抗生素方面存在显著延迟。这一研究领域值得更深入研究,以便在病程中更早地识别感染性休克。