• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

研究急诊科感染性休克患者分流治疗地点与给予适当抗生素时间之间的关联。

Examining the association between triage streamed treatment location and time to appropriate antibiotics in emergency department patients with septic shock.

作者信息

Ryan Kimberley, Greenslade Jaimi, Williams Julian

机构信息

Emergency and Trauma Centre, Royal Brisbane and Women's Hospital, Herston, Queensland, Australia.

Faculty of Health, School of Nursing, Queensland University of Technology, Brisbane, Queensland, Australia.

出版信息

Emerg Med Australas. 2020 Dec;32(6):1008-1014. doi: 10.1111/1742-6723.13552. Epub 2020 Jun 29.

DOI:10.1111/1742-6723.13552
PMID:32602254
Abstract

OBJECTIVE

Early recognition and treatment for sepsis is critical in improving patient outcomes. The present study sought to examine whether triage location was associated with time to appropriate antibiotics in a cohort of ED patients with septic shock.

METHODS

Septic shock patients were identified from a database of ED patients admitted with infection. Demographic, clinical and outcome data were reported by triage location. Time to event analyses sought to identify the association between triage location and time to appropriate antibiotic. Secondary outcome variables included ED and hospital length of stay (LOS), 30-day mortality, and ICU admission.

RESULTS

Time to appropriate antibiotic administration was longer for those patients triaged to lower acuity (242 min) compared to higher acuity (98 min, P < 0.01) locations. After adjustment for severity of illness, hospital LOS, ED LOS and 30-day mortality were similar regardless of the triaged location. Admission to ICU was lower for patients triaged to lower (7.3%) compared to higher (47.3%) acuity treatment locations.

CONCLUSIONS

We identified a sub-group of septic shock patients triaged to a lower acuity treatment location who received significant delays to antibiotics. This research area deserves closer examination to potentially recognise septic shock earlier in the continuum.

摘要

目的

早期识别和治疗脓毒症对于改善患者预后至关重要。本研究旨在探讨在一组感染性休克的急诊科(ED)患者中,分诊地点是否与使用合适抗生素的时间相关。

方法

从因感染入院的急诊科患者数据库中识别出感染性休克患者。按分诊地点报告人口统计学、临床和结局数据。事件发生时间分析旨在确定分诊地点与使用合适抗生素时间之间的关联。次要结局变量包括急诊科和住院时间(LOS)、30天死亡率和重症监护病房(ICU)入住情况。

结果

与分诊至较高 acuity(98分钟,P < 0.01)地点的患者相比,分诊至较低 acuity(242分钟)的患者使用合适抗生素的时间更长。在对疾病严重程度进行调整后,无论分诊地点如何,住院时间、急诊科住院时间和30天死亡率均相似。分诊至较低 acuity(7.3%)治疗地点的患者入住ICU的比例低于分诊至较高 acuity(47.3%)治疗地点的患者。

结论

我们识别出一组分诊至较低 acuity 治疗地点的感染性休克患者,他们在使用抗生素方面存在显著延迟。这一研究领域值得更深入研究,以便在病程中更早地识别感染性休克。

相似文献

1
Examining the association between triage streamed treatment location and time to appropriate antibiotics in emergency department patients with septic shock.研究急诊科感染性休克患者分流治疗地点与给予适当抗生素时间之间的关联。
Emerg Med Australas. 2020 Dec;32(6):1008-1014. doi: 10.1111/1742-6723.13552. Epub 2020 Jun 29.
2
The Impact of Timing of Antibiotics on Outcomes in Severe Sepsis and Septic Shock: A Systematic Review and Meta-Analysis.抗生素使用时机对严重脓毒症和脓毒性休克预后的影响:一项系统评价和Meta分析
Crit Care Med. 2015 Sep;43(9):1907-15. doi: 10.1097/CCM.0000000000001142.
3
Antibiotic Timing and Outcomes in Sepsis.抗生素时机与脓毒症结局。
Am J Med Sci. 2018 Jun;355(6):524-529. doi: 10.1016/j.amjms.2018.02.007. Epub 2018 Feb 21.
4
Impact of extended emergency department stay on antibiotic re-dosing delays and outcomes in sepsis.急诊科延长留观时间对脓毒症患者抗生素重新给药延迟及治疗结果的影响
Am J Emerg Med. 2022 May;55:32-37. doi: 10.1016/j.ajem.2022.02.028. Epub 2022 Feb 24.
5
Time Spent in the Emergency Department and Outcomes in Patients With Severe Sepsis and Septic Shock.严重脓毒症和脓毒性休克患者在急诊科的停留时间及预后
Adv Emerg Nurs J. 2018 Apr/Jun;40(2):94-103. doi: 10.1097/TME.0000000000000188.
6
Evaluation of an emergency department triage screening tool for suspected severe sepsis and septic shock.急诊科对疑似严重脓毒症和脓毒性休克的分诊筛查工具的评估。
J Healthc Qual. 2014 Jan-Feb;36(1):52-61; quiz 59-61. doi: 10.1111/jhq.12055.
7
Evaluation of electronic measurement of capillary refill for Sepsis screening at ED triage.电子测量毛细血管再充盈时间在 ED 分诊中用于脓毒症筛查的评估。
Am J Emerg Med. 2023 Aug;70:61-65. doi: 10.1016/j.ajem.2023.05.009. Epub 2023 May 11.
8
Antibiotic Timing and Progression to Septic Shock Among Patients in the ED With Suspected Infection.急诊疑似感染患者抗生素时机与脓毒性休克进展。
Chest. 2022 Jan;161(1):112-120. doi: 10.1016/j.chest.2021.06.029. Epub 2021 Jun 26.
9
The DISPARITY-II study: delays to antibiotic administration in women with severe sepsis or septic shock.DISPARITY-II研究:重症脓毒症或脓毒性休克女性患者抗生素给药延迟情况
Acad Emerg Med. 2014 Dec;21(12):1499-502. doi: 10.1111/acem.12546. Epub 2014 Nov 25.
10
INITIAT-E.D.: Impact of timing of INITIation of Antibiotic Therapy on mortality of patients presenting to an Emergency Department with sepsis.抗生素治疗起始时机对因脓毒症就诊于急诊科患者死亡率的影响。
Emerg Med Australas. 2015 Jun;27(3):196-201. doi: 10.1111/1742-6723.12394. Epub 2015 Apr 6.

引用本文的文献

1
Expression of inflammatory factors and distribution of pathogens in patients with septic shock and their correlation with prognosis: a cross-sectional study.脓毒症休克患者炎症因子表达及病原菌分布情况及其与预后的相关性:一项横断面研究
Rev Inst Med Trop Sao Paulo. 2025 Jul 7;67:e45. doi: 10.1590/S1678-9946202567045. eCollection 2025.
2
Risk classification and door-to-antibiotic time in patients with suspected sepsis.疑似脓毒症患者的风险分类和抗生素治疗开始时间。
Rev Lat Am Enfermagem. 2023 Dec 4;31:e4064. doi: 10.1590/1518-8345.6635.4064. eCollection 2023.