Division of Cancer Statistics Integration, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan.
Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.
Jpn J Clin Oncol. 2020 Sep 28;50(10):1218-1224. doi: 10.1093/jjco/hyaa094.
The main objective of this study was to estimate the cumulative mortality risk for lung cancer according to smoking status and exposure to secondhand smoke (SHS) in Japan. We applied a life-table method to estimate the cumulative risk. Estimated lifetime cumulative risk for 20-year-old non-smokers, former, and current smokers was 3.2%, 7.6%, and 14.9% for men and 1.9%, 5.6%, and 7.2% for women, respectively. For males, the estimated risk was 3.2% for non-smokers not exposed to SHS and 4.1% for non-smokers exposed to SHS. For females, the estimated risk was 1.9% for non-smokers not exposed to SHS and 2.4% for non-smokers exposed to SHS. Lifetime cumulative mortality risk differed greatly according to smoking status. Moreover, SHS exposure resulted in observable differences in lifetime mortality risk. This study may be useful for the development of tailored prevention programs.
本研究的主要目的是评估日本人群中根据吸烟状况和二手烟（SHS）暴露情况估算的肺癌累积死亡率。我们应用寿命表法来估算累积风险。估算 20 岁时不吸烟者、曾经吸烟者和当前吸烟者的终生累积风险分别为男性 3.2%、7.6%和 14.9%，女性 1.9%、5.6%和 7.2%。对于男性，未暴露于 SHS 的不吸烟者的估计风险为 3.2%，而暴露于 SHS 的不吸烟者的估计风险为 4.1%。对于女性，未暴露于 SHS 的不吸烟者的估计风险为 1.9%，而暴露于 SHS 的不吸烟者的估计风险为 2.4%。终生累积死亡率根据吸烟状况有很大差异。此外，SHS 暴露导致终生死亡率有明显差异。本研究可能有助于制定有针对性的预防计划。
