School of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou, China.
Food Innovation and Health Programme, Quadram Institute Bioscience, Norwich Research Park, Norwich, UK.
Crit Rev Food Sci Nutr. 2021;61(16):2742-2755. doi: 10.1080/10408398.2020.1784841. Epub 2020 Jun 30.
Gastric emptying refers to a process in which the stomach discharges its contents into the small intestine to further digest and absorb nutrients. Understanding the mechanisms of gastric emptying and relationships between food and individuals is of paramount importance for the design and manufacture of novel and healthy foods. For ethical and cost reasons, in vivo tests are not always possible. In vitro digestion models therefore play a key role in current exploration of gastric emptying. This review outlines the mechanisms and physiology of gastric emptying, including calories, viscosity, composition of the food, age and gender of the individual. In addition, recent progress on in vitro static and dynamic gastric digestion models and future research trends are included in this review.
胃排空是指胃将其内容物排入小肠以进一步消化和吸收营养的过程。了解胃排空的机制和食物与个体之间的关系对于设计和制造新型健康食品至关重要。出于伦理和成本原因，并非总是可以进行体内测试。因此，体外消化模型在当前对胃排空的研究中起着关键作用。本文综述了胃排空的机制和生理学，包括热量、粘度、食物组成、个体的年龄和性别。此外，本文还介绍了近年来静态和动态体外胃消化模型的研究进展及未来研究趋势。
