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Transforming Diagnostics in Lung Transplantation: From Bronchoscopy to an Artificial Intelligence-driven Approach.

作者信息

Shigemura Norihisa

机构信息

Division of Cardiovascular SurgeryTemple University Health SystemPhiladelphia, Pennsylvania.

出版信息

Am J Respir Crit Care Med. 2020 Aug 15;202(4):486-488. doi: 10.1164/rccm.202005-1821ED.

DOI:10.1164/rccm.202005-1821ED
PMID:32603183
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7427394/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5627/7427394/01b1a7836f7e/rccm.202005-1821EDf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5627/7427394/01b1a7836f7e/rccm.202005-1821EDf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5627/7427394/01b1a7836f7e/rccm.202005-1821EDf1.jpg

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Transforming Diagnostics in Lung Transplantation: From Bronchoscopy to an Artificial Intelligence-driven Approach.肺移植诊断的变革：从支气管镜检查到人工智能驱动的方法。
Am J Respir Crit Care Med. 2020 Aug 15;202(4):486-488. doi: 10.1164/rccm.202005-1821ED.
2
[Application of flexible bronchoscopy in postoperative management of lung transplantation].
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3
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Chest. 2024 Feb;165(2):e60-e61. doi: 10.1016/j.chest.2023.09.034.
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Flexible bronchoscopy in lung transplantation.肺移植中的可弯曲支气管镜检查
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Motivation and Learning: Leveraging Artificial Intelligence to Improve Bronchoscopy Performance.动机与学习：利用人工智能提升支气管镜检查性能
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Results of surveillance bronchoscopy after cadaveric lung transplantation: a Japanese single-institution study.尸体肺移植术后监测支气管镜检查结果：一项日本单机构研究。
Transplant Proc. 2014 Apr;46(3):944-7. doi: 10.1016/j.transproceed.2013.10.055.
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The higher risk of bleeding in lung transplant recipients from bronchoscopy is independent of traditional bleeding risks: results of a prospective cohort study.肺移植受者因支气管镜检查导致出血的较高风险独立于传统出血风险：一项前瞻性队列研究的结果
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Sedative drug requirements during bronchoscopy are higher in cystic fibrosis after lung transplantation.肺移植术后的囊性纤维化患者在支气管镜检查期间对镇静药物的需求量更高。
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J Clin Med. 2025 Apr 16;14(8):2729. doi: 10.3390/jcm14082729.
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ERS Congress 2024: highlights from the Thoracic Surgery and Lung Transplantation Assembly.2024年欧洲呼吸学会大会：胸外科与肺移植大会亮点
ERJ Open Res. 2025 Jan 27;11(1). doi: 10.1183/23120541.01046-2024. eCollection 2025 Jan.
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Personalized risk predictor for acute cellular rejection in lung transplant using soluble CD31.

本文引用的文献

1
Risk Factors for Acute Rejection in the First Year after Lung Transplant. A Multicenter Study.肺移植后第一年急性排斥反应的危险因素。一项多中心研究。
Am J Respir Crit Care Med. 2020 Aug 15;202(4):576-585. doi: 10.1164/rccm.201910-1915OC.
2
High levels of dd-cfDNA identify patients with TCMR 1A and borderline allograft rejection at elevated risk of graft injury.高水平的 dd-cfDNA 可识别 1A 型 TCMR 和边缘供体排斥反应患者，这些患者有发生移植物损伤的高风险。
Am J Transplant. 2020 Sep;20(9):2491-2498. doi: 10.1111/ajt.15822. Epub 2020 Mar 10.
3
Early reduction of regulatory T cells is associated with acute rejection in liver transplantation under tacrolimus-based immunosuppression with basiliximab induction.
使用可溶性 CD31 对肺移植后急性细胞排斥反应进行个体化风险预测
Sci Rep. 2022 Oct 21;12(1):17628. doi: 10.1038/s41598-022-21070-1.
在使用巴利昔单抗诱导的基于他克莫司的免疫抑制治疗下，肝移植中调节性T细胞的早期减少与急性排斥反应相关。
Am J Transplant. 2020 Aug;20(8):2058-2069. doi: 10.1111/ajt.15789. Epub 2020 Feb 6.
4
Increased frequency of CD4 CD25 CD127 T cells early after lung transplant is associated with improved graft survival - a retrospective study.肺移植后早期 CD4 CD25 CD127 T 细胞频率增加与移植物存活率提高相关——一项回顾性研究。
Transpl Int. 2020 May;33(5):503-516. doi: 10.1111/tri.13568. Epub 2020 Jan 31.
5
Elderly patients with multiple comorbidities: insights from the bedside to the bench and programmatic directions for this new challenge in lung transplantation.老年合并多种共病患者：从床边到研究平台获得的见解，以及肺移植领域这一全新挑战的规划方向。
Transpl Int. 2020 Apr;33(4):347-355. doi: 10.1111/tri.13533. Epub 2019 Oct 31.
6
The emerging role of regulatory T cells following lung transplantation.肺移植后调节性 T 细胞的新作用。
Immunol Rev. 2019 Nov;292(1):194-208. doi: 10.1111/imr.12801. Epub 2019 Sep 19.
7
Vendor-specific microbiome controls both acute and chronic murine lung allograft rejection by altering CD4 Foxp3 regulatory T cell levels.特定供体的微生物组通过改变 CD4 Foxp3 调节性 T 细胞水平来控制急性和慢性小鼠肺移植排斥反应。
Am J Transplant. 2019 Oct;19(10):2705-2718. doi: 10.1111/ajt.15523. Epub 2019 Aug 2.
8
Human FOXP3 Regulatory T Cell Heterogeneity and Function in Autoimmunity and Cancer.人类 FOXP3 调节性 T 细胞在自身免疫和癌症中的异质性和功能。
Immunity. 2019 Feb 19;50(2):302-316. doi: 10.1016/j.immuni.2019.01.020.
9
Bronchus-associated lymphoid tissue-resident Foxp3+ T lymphocytes prevent antibody-mediated lung rejection.气道相关淋巴组织驻留的 Foxp3+T 淋巴细胞可预防抗体介导的肺排斥反应。
J Clin Invest. 2019 Feb 1;129(2):556-568. doi: 10.1172/JCI122083. Epub 2018 Dec 18.
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Prolongation of allograft survival by passenger donor regulatory T cells.过客供者调节性 T 细胞延长移植物存活时间。
Am J Transplant. 2019 May;19(5):1371-1379. doi: 10.1111/ajt.15212. Epub 2019 Feb 5.