Student Wellness and Counselling Centre, UC-5000, Memorial University of Newfoundland, St John's, NL, A1C 5S7, Canada.
Student Wellness and Counselling Centre, Memorial University of Newfoundland, St John's, Newfoundland, Canada.
J Clin Psychiatry. 2020 Jun 23;81(4):19r13085. doi: 10.4088/JCP.19r13085.
To estimate the worldwide prevalence of obsessive-compulsive disorder (OCD), examine whether women are at greater risk than men, and explore other potential moderators of OCD prevalence to explain variability in community-based epidemiologic studies.
An electronic search of PsycINFO and PubMed was conducted until January 2017, without date or language restrictions, using the keywords OCD, epidemiology, and prevalence. The search was supplemented by articles referenced in the obtained sources and relevant reviews.
Studies were included if they reported current, period, and/or lifetime OCD prevalence (diagnosed according to an interview based on DSM or ICD criteria) in representative community samples of adults aged 18 years or older. A total of 4,045 studies were retrieved, with 34 studies ultimately included.
OCD prevalence was extracted from each study alongside 9 moderators: gender, year, response rate, region, economic status, diagnostic criteria, diagnostic interview, interviewer, and age.
The overall aggregate current, period, and lifetime OCD prevalence estimates were 1.1%, 0.8%, and 1.3%, respectively. In a typical sample, women were 1.6 times more likely to experience OCD compared to men, with lifetime prevalence rates of 1.5% in women and 1.0% in men. There was also a trend toward younger adults' being more likely to experience OCD in their lifetime than older adults. All findings demonstrated moderate heterogeneity.
Women are typically at greater risk of experiencing OCD in their lifetime than men.
估计全世界强迫症（OCD）的患病率，考察女性是否比男性面临更大的患病风险，并探讨 OCD 患病率的其他潜在调节因素，以解释基于社区的流行病学研究中的变异性。
对 PsycINFO 和 PubMed 进行了电子检索，检索时间截至 2017 年 1 月，未设置日期或语言限制，使用的关键词为 OCD、流行病学和患病率。通过获取来源中引用的文章和相关综述对检索进行了补充。
如果研究报告了目前、期间和/或终生 OCD 患病率（根据基于 DSM 或 ICD 标准的访谈进行诊断），且研究对象为年龄在 18 岁及以上的代表性社区成年人，则将其纳入研究。共检索到 4045 篇文章，最终纳入 34 篇文章。
从每项研究中提取 OCD 患病率以及 9 个调节因素：性别、年份、应答率、地区、经济状况、诊断标准、诊断访谈、访谈者和年龄。
目前、期间和终生 OCD 的总体综合患病率估计值分别为 1.1%、0.8%和 1.3%。在典型样本中，女性终生患 OCD 的风险比男性高 1.6 倍，女性的终生患病率为 1.5%，男性为 1.0%。也存在年轻人比老年人更有可能在一生中经历 OCD 的趋势。所有发现均表现出中度异质性。
女性一生中患 OCD 的风险通常比男性更高。
