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新冠病毒肺炎患者的精神病性症状。一项回顾性描述性研究。

Psychotic symptoms in COVID-19 patients. A retrospective descriptive study.

作者信息

Parra A, Juanes A, Losada C P, Álvarez-Sesmero S, Santana V D, Martí I, Urricelqui J, Rentero D

机构信息

Servicio de Psiquiatría, Hospital Universitario 12 de Octubre, Madrid, Spain.

Servicio de Psiquiatría, Hospital Universitario 12 de Octubre, Madrid, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Vigo, Spain; MRcPsych. Royal College of Psychiatrist, London, United Kingdom.

出版信息

Psychiatry Res. 2020 Sep;291:113254. doi: 10.1016/j.psychres.2020.113254. Epub 2020 Jun 24.

Abstract

Psychotic symptoms have been related to other coronavirus infections. We conducted a single-centre retrospective and observational study to describe new-onset psychotic episodes in COVID-19 patients. Ten patients infected by the novel coronavirus with psychotic symptoms and no previous history of psychosis were identified by the emergency and liaison psychiatry departments. Nine of the cases presented with psychotic symptoms at least two weeks after the first somatic manifestations attributed to COVID-19 and receiving pharmacological treatment. Structured delusions mixed with confusional features were the most frequent clinical presentations. Hence, COVID-19 patients can develop psychotic symptoms as a consequence of multiple concurrent factors.

摘要

精神病性症状已与其他冠状病毒感染有关。我们进行了一项单中心回顾性观察研究,以描述新冠肺炎患者新出现的精神病性发作。急诊科和联络精神科确定了10例感染新型冠状病毒且有精神病性症状但既往无精神病病史的患者。其中9例在首次出现归因于新冠肺炎的躯体表现并接受药物治疗至少两周后出现精神病性症状。结构化妄想伴混乱特征是最常见的临床表现。因此,新冠肺炎患者可因多种并发因素而出现精神病性症状。

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