Department of Diagnosis and Surgery Clinic.
Oral and Maxillofacial Surgery, Department of Diagnosis and Surgery, Aracatuba School of Dentistry, Sao Paulo State University, Aracatuba.
J Craniofac Surg. 2020 Sep;31(6):e593-e595. doi: 10.1097/SCS.0000000000006662.
Toxic epidermal necrolyses represent a severe epidermolytic reaction characterized by cutaneous erythema and target lesions affecting >30% of the body surface, skin, and mucous membranes. Ulcerative lesions on the labial mucosa may evolve during healing, resulting in rare complications, such as lip adhesions. This report shows the successful treatment of a lip synechia resulting from the healing of mucosal lesions in a patient with toxic epidermal necrolysis caused by the use of Lamotrigine and Ibuprofen. Although the treatment of the presented lip synechia was simple, this sequela can be avoided by measures such as hydration, hygiene and lip lubrication.
中毒性表皮坏死松解症表现为一种严重的表皮松解反应，其特征为皮肤红斑和靶形病变，影响全身表面积>30%、皮肤和黏膜。唇黏膜的溃疡性病变在愈合过程中可能会进展，导致罕见的并发症，如唇粘连。本报告展示了一例因使用拉莫三嗪和布洛芬引起中毒性表皮坏死松解症而导致的黏膜病变愈合后出现的唇粘连的成功治疗。尽管该唇粘连的治疗很简单，但通过保持水分、卫生和唇部润滑等措施可以避免这种后遗症。
