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含硅烷钴氧化物纳米颗粒的高透氧性眼科生物材料的特性与相容性研究。

Characterization and Compatibility of High Oxygen Permeable Ophthalmic Biomaterial Containing Silane with Cobalt Oxide Nanoparticles.

机构信息

Department of Optometry & Vision Science, Daegu Catholic University, Gyeongsan, 38430, South Korea.

出版信息

J Nanosci Nanotechnol. 2020 Nov 1;20(11):6954-6958. doi: 10.1166/jnn.2020.18819.

Abstract

This research is conducted to analyze the compatibility of used monomers and produce the high functional hydrogel ophthalmic polymer containing silane and nanoparticles. Vinyltrimethoxysilane (VTMS) and cobalt oxide nanoparticles are used as additives for the basic combination of silicone monomer (Sil-H) and methyl methacrylate (MMA). And also, the materials are copolymerized with ethylene glycol dimethacrylate (EGDMA) as the cross-linking agent, photo polymerization initiator (2H2M) as the initiator. It is judged that the lenses of all combinations are optically excellent and thus have good compatibility. Measurement of the optical and physical characteristics of the manufactured hydrophilic ophthalmic polymer are different in each case. Especially VTMS with cobalt oxide nanoparticle increases the oxygen permeability by the addition of cobalt nanoparticles. These materials are considered to make synergy effect each other, so it can be used in functional hydrogel ophthalmic lenses.

摘要

本研究旨在分析使用的单体的相容性,并制备含有硅烷和纳米粒子的高功能水凝胶眼科用聚合物。乙烯基三甲氧基硅烷(VTMS)和氧化钴纳米粒子被用作硅酮单体(Sil-H)和甲基丙烯酸甲酯(MMA)基本组合的添加剂。此外,还将这些材料与乙二醇二甲基丙烯酸酯(EGDMA)共聚作为交联剂,2H2M 作为引发剂。判断所有组合的镜片在光学上都是优秀的,因此具有良好的相容性。制造的亲水性眼科用聚合物的光学和物理特性的测量在每种情况下都是不同的。特别是含有钴纳米粒子的 VTMS 通过添加钴纳米粒子增加了氧气透过率。这些材料被认为彼此具有协同效应,因此可以用于功能性水凝胶眼科镜片。

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