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对于出生在非洲且居住在明尼苏达州的艾滋病毒感染者而言,服用抗逆转录病毒药物的意义。

The Significance of Taking Antiretroviral Medications for African-Born People Living with HIV and Residing in Minnesota.

作者信息

Cernasev Alina, Larson William L, Peden-McAlpine Cynthia, Rockwood Todd, Ranelli Paul L, Okoro Olihe, Schommer Jon C

机构信息

College of Pharmacy, The University of Tennessee Health Science Center, 301 S Perimeter Park Drive, Suite 220, Nashville, TN 37211, USA.

Allina Health Uptown Clinic, 1221 West Lake St., Suite 201, Minneapolis, MN 55455, USA.

出版信息

Pharmacy (Basel). 2020 Jun 26;8(2):108. doi: 10.3390/pharmacy8020108.

DOI:10.3390/pharmacy8020108
PMID:32604973
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7355956/
Abstract

Thanks to the development of antiretroviral (ART) medications, HIV is now a chronic and manageable disease. This study aimed to (1) capture the experiences of African-born persons living with HIV and taking antiretroviral treatment, and (2) explore the impact of social and cultural factors on their decisions to follow the prescribed treatment. For this study, a qualitative approach was used. The participants were recruited via fliers, then screened for inclusion and exclusion criteria. Recruitment of the participants continued until data saturation occurred. The interview guide was developed based on the extensive literature and recommendations from the clinical team. In-person narrative interviews were conducted with 14 participants-African-born persons living with HIV and residing in Minnesota. Thematic Analysis revealed three emergent themes: ""; barriers and facilitators in taking ART medications; and the power of spirituality and prayers. The findings of this study paint a picture of African-born persons living with HIV, and their experiences with ART medications. This study not only presents the participants' medication experiences and their significance, but also tells their stories of how God and prayers play a significant role in helping them to get through the difficult moments of their lives.

摘要

得益于抗逆转录病毒(ART)药物的发展,如今艾滋病已成为一种可慢性管理的疾病。本研究旨在:(1)了解出生于非洲且感染艾滋病毒并接受抗逆转录病毒治疗者的经历;(2)探讨社会和文化因素对他们遵医嘱治疗决策的影响。本研究采用质性研究方法。通过传单招募参与者,然后根据纳入和排除标准进行筛选。参与者的招募持续到数据饱和。访谈指南是根据大量文献和临床团队的建议制定的。对14名参与者——出生于非洲、感染艾滋病毒且居住在明尼苏达州的人——进行了面对面的叙事访谈。主题分析揭示了三个新出现的主题:服用抗逆转录病毒药物的障碍和促进因素;以及灵性和祈祷的力量。本研究结果描绘了出生于非洲的艾滋病毒感染者及其使用抗逆转录病毒药物的经历。本研究不仅呈现了参与者的用药经历及其重要性,还讲述了他们关于上帝和祈祷如何在帮助他们度过人生艰难时刻中发挥重要作用的故事。

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Pharmacy (Basel). 2020 May 30;8(2):92. doi: 10.3390/pharmacy8020092.
2
Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults: 2018 Recommendations of the International Antiviral Society-USA Panel.抗逆转录病毒药物治疗和预防成人 HIV 感染:美国国际抗病毒学会 2018 年推荐意见。
JAMA. 2018 Jul 24;320(4):379-396. doi: 10.1001/jama.2018.8431.
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Bictegravir, emtricitabine, and tenofovir alafenamide versus dolutegravir, abacavir, and lamivudine for initial treatment of HIV-1 infection (GS-US-380-1489): a double-blind, multicentre, phase 3, randomised controlled non-inferiority trial.比克替拉韦、恩曲他滨和替诺福韦艾拉酚胺与多替拉韦、阿巴卡韦和拉米夫定用于治疗人类免疫缺陷病毒 1 型感染的初始治疗(GS-US-380-1489):一项双盲、多中心、3 期、随机、对照非劣效性试验。
Lancet. 2017 Nov 4;390(10107):2063-2072. doi: 10.1016/S0140-6736(17)32299-7. Epub 2017 Aug 31.
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The Experience of Antiretroviral Treatment for Black West African Women who are HIV Positive and Living in London: An Interpretative Phenomenological Analysis.对感染艾滋病毒且生活在伦敦的西非黑人女性进行抗逆转录病毒治疗的体验:一项诠释现象学分析
AIDS Behav. 2016 Sep;20(9):2151-63. doi: 10.1007/s10461-015-1274-9.
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