Rodriguez Chelsea, Salas Natalie Mariam, Begay-Bruno Matthew, Brett Meghan, Byrd Tom F, Ruan Lucy, Jakeman Bernadette
Department of Pharmacy, 21764University of New Mexico Hospitals, Albuquerque, NM, USA.
Department of Internal Medicine, Division of Infectious Diseases, 1104University of New Mexico Hospitals, Albuquerque, NM, USA.
Int J STD AIDS. 2023 Apr;34(5):355-360. doi: 10.1177/09564624221151090. Epub 2023 Jan 11.
Nontuberculosis mycobacterium are increasingly being identified as sources of disseminated infections in immunocompromised patients. These infections can be challenging to identify and treat due complexities of diagnosis and inherent resistance to many medications. We present two cases of patients with human immunodeficiency virus who had infections, complicated by immune reconstruction inflammatory syndrome (IRIS). We also present a review of the English literature surrounding the disease, including reported resistance patterns to antimicrobial therapy, which can be highly variable.
非结核分枝杆菌越来越多地被确认为免疫功能低下患者播散性感染的来源。由于诊断的复杂性以及对多种药物的固有耐药性，这些感染的识别和治疗可能具有挑战性。我们报告了两例感染人类免疫缺陷病毒的患者，他们的感染因免疫重建炎症综合征（IRIS）而复杂化。我们还对围绕该疾病的英文文献进行了综述，包括报告的对抗菌治疗的耐药模式，其可能差异很大。
