Grimminck Koen, Santegoets Lindy Anne Maria, Siemens Frederike Charlotte, Fraaij Pieter Leendert Alex, Reiss Irwin Karl Marcel, Schoenmakers Sam
Department of Obstetrics and Gynaecology, Reinier de Graaf Gasthuis, Delft, Zuid-Holland, The Netherlands.
Department of Paediatrics, Subdivision Infectious Diseases and Immunology, Erasmus Medical Center - Sophia, Rotterdam, The Netherlands.
BMJ Case Rep. 2020 Jun 30;13(6):e235581. doi: 10.1136/bcr-2020-235581.
We present a case of a 38+1 weeks pregnant patient (G1P0) with a proven COVID-19 infection, who was planned for induction of labour because of pre-existent hypertension, systemic lupus erythematosus, respiratory problem of coughing and mild dyspnoea without fever during the COVID-19 pandemic in March 2020. To estimate the risk of vertical transmission of Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) during labour and delivery, we collected oropharyngeal, vaginal, urinary, placental and neonatal PCRs for SARS-CoV-2 during the period of admission. All PCRs, except for the oropharyngeal, were negative and vertical transmission was not observed. Labour and delivery were uncomplicated and the patient and neonate were discharged the next day. We give a short overview of the known literature about SARS-CoV-2-related infection during pregnancy, delivery and outcome of the neonate.
我们报告一例38 + 1周妊娠患者（G1P0），确诊感染新型冠状病毒肺炎（COVID - 19）。该患者因既往高血压、系统性红斑狼疮、咳嗽及轻度呼吸困难等呼吸问题，且在2020年3月COVID - 19大流行期间无发热症状，计划引产。为评估严重急性呼吸综合征冠状病毒2（SARS-CoV-2）在分娩过程中的垂直传播风险，我们在入院期间收集了患者的口咽、阴道、尿液、胎盘及新生儿的SARS-CoV-2聚合酶链反应（PCR）样本。除口咽样本外，所有PCR检测结果均为阴性，未观察到垂直传播情况。分娩过程顺利，患者及新生儿于次日出院。我们简要概述了关于妊娠、分娩期间SARS-CoV-2相关感染及新生儿结局的已知文献。
