脑出血与新型冠状病毒肺炎：关联还是因果关系。
Intracerebral Hemorrhage and SARS-CoV-2: Association or Causation.
作者信息
Agarwal Ayush, Vishnu Venugopalan Y, Vibha Deepti, Bhatia Rohit, Gupta Anu, Das Animesh, Srivastava M V Padma
机构信息
Department of Neurology, AIIMS, New Delhi, India.
出版信息
Ann Indian Acad Neurol. 2020 May-Jun;23(3):261-264. doi: 10.4103/aian.AIAN_362_20. Epub 2020 Jun 5.
BACKGROUND
Recent respiratory infection including SARS-CoV-2 is an independent risk factor for acute cerebrovascular disease.
PURPOSE
There have been reports linking haemorrhagic strokes to SARS-CoV-2 infection during this pandemic, which lead us to evaluate if SARS-CoV-2 infection could be associated with increased risk of intracerebral haemorrhage (ICH).
METHODS
A retrospective observational study evaluating all stroke cases admitted in our centre in the past one month.
RESULTS
More than half (56%) had ICH, compared to 22% last year. Two patients with ICH were SARS-CoV-2 positive and they had no or mild respiratory symptoms and had higher occurrence of renal dysfunction.
CONCLUSION
There could be possible association between ICH and SARS-CoV-2 infections. However, a prospective study with larger sample size is needed to elucidate the pathogenesis.
背景
近期包括新型冠状病毒（SARS-CoV-2）在内的呼吸道感染是急性脑血管疾病的独立危险因素。
目的
在本次大流行期间，有报告将出血性卒中与SARS-CoV-2感染联系起来，这促使我们评估SARS-CoV-2感染是否可能与脑出血（ICH）风险增加有关。
方法
一项回顾性观察研究，评估过去一个月在我们中心收治的所有卒中病例。
结果
超过一半（56%）的患者发生脑出血，而去年这一比例为22%。两名脑出血患者新型冠状病毒检测呈阳性，他们没有或仅有轻微呼吸道症状，且肾功能不全的发生率较高。
结论
脑出血与新型冠状病毒感染之间可能存在关联。然而，需要进行更大样本量的前瞻性研究来阐明其发病机制。
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