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视盘小凹性黄斑病变:当前的管理策略

Optic disk pit maculopathy: current management strategies.

作者信息

Chatziralli Irini, Theodossiadis Panagiotis, Theodossiadis George P

机构信息

2nd Department of Ophthalmology, University of Athens, Attikon Hospital, Athens, Greece,

出版信息

Clin Ophthalmol. 2018 Aug 10;12:1417-1422. doi: 10.2147/OPTH.S153711. eCollection 2018.

Abstract

INTRODUCTION

Optic disk pit (ODP) is a rare congenital abnormality of the optic nerve head and can lead to visual impairment when macular detachment occurred. Recent advances in retinal imaging brought new insights into the pathophysiology of the disease, while new therapeutic options have been also described.

METHODS

We made a comprehensive search of the literature regarding the current treatment modalities for the treatment of ODP maculopathy.

RESULTS

Although there have been reported some cases of spontaneous resolution, current management of ODP maculopathy involves several surgical approaches. The most commonly used treatment alternative for ODP maculopathy management is vitrectomy, either alone or in combination with other treatment modalities, such as gas tamponade or laser photocoagulation. Other options, such as scleral buckling and inner fenestration, are also used, based on the recent findings about pathophysiology of the disease.

CONCLUSION

The management of ODP maculopathy remains challenging. Even though there are further advances in the understanding of the disease pathophysiology, the applied treatment is not single and therapeutic modalities differ in the success rate, related to the anatomical and functional results.

摘要

引言

视盘小凹(ODP)是一种罕见的视神经乳头先天性异常,当黄斑发生脱离时可导致视力损害。视网膜成像技术的最新进展为该疾病的病理生理学带来了新的见解,同时也描述了新的治疗选择。

方法

我们对有关ODP黄斑病变当前治疗方式的文献进行了全面检索。

结果

尽管有一些自发缓解的病例报道,但目前ODP黄斑病变的治疗涉及多种手术方法。ODP黄斑病变管理中最常用的治疗选择是玻璃体切除术,可单独使用或与其他治疗方式联合使用,如气体填塞或激光光凝。根据该疾病病理生理学的最新发现,其他选择,如巩膜扣带术和内开窗术,也被采用。

结论

ODP黄斑病变的管理仍然具有挑战性。尽管在疾病病理生理学的理解方面有进一步进展,但应用的治疗方法并不单一,且治疗方式在成功率方面存在差异,这与解剖和功能结果有关。

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