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慢性阻塞性肺疾病(COPD)患者骨折风险的管理:通过医疗专业人员和患者参与达成英国共识

Management of Fracture Risk in Patients with Chronic Obstructive Pulmonary Disease (COPD): Building a UK Consensus Through Healthcare Professional and Patient Engagement.

作者信息

Gupta Ayushman, Jayes Leah R, Holmes Steve, Sahota Opinder, Canavan Melissa, Elkin Sarah L, Lim Kelvin, Murphy Anna C, Singh Sally, Towlson Elizabeth A, Ward Helen, Scullion Jane, McKeever Tricia M, Bolton Charlotte E

机构信息

NIHR Nottingham BRC Respiratory Theme, School of Medicine, University of Nottingham, City Hospital Campus, Nottingham, UK.

Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, City Hospital Campus, Nottingham, UK.

出版信息

Int J Chron Obstruct Pulmon Dis. 2020 Jun 15;15:1377-1390. doi: 10.2147/COPD.S233398. eCollection 2020.

Abstract

INTRODUCTION

Osteoporosis and bone fractures are common in chronic obstructive pulmonary disease (COPD) and contribute significantly to morbidity and mortality. Current national guidance on COPD management recommends addressing bone health in patients, however, does not detail how. This consensus outlines key elements of a structured approach to managing bone health and fracture risk in patients with COPD.

METHODS

A systematic approach incorporating multifaceted methodologies included detailed patient and healthcare professional (HCP) surveys followed by a roundtable meeting to reach a consensus on what a pathway would look like.

RESULTS

The surveys revealed that fracture risk was not always assessed despite being recognised as an important aspect of COPD management by HCPs. The majority of the patients also stated they would be receptive to discussing treatment options if found to be at risk of osteoporotic fractures. Limited time and resource allocation were identified as barriers to addressing bone health during consultations. The consensus from the roundtable meeting was that a proactive systematic approach to assessing bone health should be adopted. This should involve using fracture risk assessment tools to identify individuals at risk, investigating secondary causes of osteoporosis if a diagnosis is made and reinforcing non-pharmacological and preventative measures such as smoking cessation, keeping active and pharmacological management of osteoporosis and medicines management of corticosteroid use. Practically, prioritising patients with important additional risk factors, such as previous fragility fractures, older age and long-term oral corticosteroid use for an assessment, was felt required.

CONCLUSION

There is a need for integrating fracture risk assessment into the COPD pathway. Developing a systematic and holistic approach to addressing bone health is key to achieving this. In tandem, opportunities to disseminate the information and educational resources are also required.

摘要

引言

骨质疏松症和骨折在慢性阻塞性肺疾病(COPD)中很常见,对发病率和死亡率有重大影响。目前关于COPD管理的国家指南建议关注患者的骨骼健康,但未详细说明如何操作。本共识概述了在COPD患者中管理骨骼健康和骨折风险的结构化方法的关键要素。

方法

采用一种包含多方面方法的系统方法,包括详细的患者和医疗保健专业人员(HCP)调查,随后召开圆桌会议,就一条路径的样子达成共识。

结果

调查显示,尽管HCP认为骨折风险是COPD管理的一个重要方面,但并非总是进行评估。大多数患者还表示,如果发现有骨质疏松性骨折风险,他们愿意讨论治疗方案。有限的时间和资源分配被确定为在会诊期间关注骨骼健康的障碍。圆桌会议的共识是,应采用积极主动的系统方法来评估骨骼健康。这应包括使用骨折风险评估工具来识别有风险的个体,如果做出诊断,调查骨质疏松症的继发原因,并加强非药物和预防措施,如戒烟、保持活跃以及骨质疏松症的药物管理和皮质类固醇使用的药物管理。实际上,认为需要优先对有重要额外风险因素的患者进行评估,如既往脆性骨折、老年和长期口服皮质类固醇使用。

结论

有必要将骨折风险评估纳入COPD诊疗路径。制定一种系统、全面的方法来解决骨骼健康问题是实现这一目标的关键。同时,也需要有传播信息和教育资源的机会。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d11/7311204/e8df63bf08c2/COPD-15-1377-g0001.jpg

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