西非感染艾滋病毒的成年人接受抗逆转录病毒治疗第一年期间的结核病发病率
Incidence of Tuberculosis During the First Year of Antiretroviral Treatment in West African HIV-Infected Adults.
作者信息
Tchakounte Youngui Boris, Coffie Patrick, Messou Eugène, Poda Armel, Fortes Deguenonvo Louise, Hawerlander Denise, Minga Albert, Balestre Eric, Dabis François, Marcy Olivier
机构信息
University of Bordeaux, Bordeaux School of Public Health, ISPED, Bordeaux, France.
Programme PACCI, site ANRS, Abidjan, Cote D'Ivoire.
出版信息
Open Forum Infect Dis. 2020 Jun 2;7(6):ofaa203. doi: 10.1093/ofid/ofaa203. eCollection 2020 Jun.
Abstract
We estimated tuberculosis incidence during the first year on antriretroviral therapy without isoniazid-preventive treatment in 6938 West African HIV-infected adults at 3.33 cases per 100 person-years (95% CI, 2.85-3.80). In multivariate Poisson models, sites in Cote d'Ivoire, male gender, low body mass index, low hemoglobin, low CD4 count, and young age were significantly associated with higher incidence.
摘要
我们估计，在未接受异烟肼预防性治疗的情况下，6938名西非感染艾滋病毒的成年人接受抗逆转录病毒治疗的第一年结核病发病率为每100人年3.33例（95%置信区间，2.85 - 3.80）。在多变量泊松模型中，科特迪瓦的地区、男性、低体重指数、低血红蛋白、低CD4细胞计数和年轻与较高发病率显著相关。
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